Clinical features and predisposing factors of delirium due to COVID-19 pneumonia in intensive care units

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dc.authoridTASCI, ILKER/0000-0002-0936-2476
dc.contributor.authorEkmekyapar, T.
dc.contributor.authorEkmekyapar, M.
dc.contributor.authorTasci, I
dc.contributor.authorSahin, L.
dc.contributor.authorDelen, L. A.
dc.date.accessioned2024-08-04T20:57:26Z
dc.date.available2024-08-04T20:57:26Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: Delirium is an acute disorder in which attention, perception, memory, thought, mood, psychomotor activity and sleep-wake cycles change rapidly. Delirium is also a common clinical syndrome in patients hospitalized in intensive care units due to COVID-19 pneumonia. We reviewed clinical features and predisposing factors of delirium according to psychomotor subtype in patients hospitalized in the intensive care units due to COVID-19 pneumonia. PATIENTS AND METHODS: 64 patients who were hospitalized in the intensive care units due to COVID-19 pneumonia were included. Delirium status and psychomotor subtype were determined by applying the Confusion Assessment Method for the Intensive Care Unit scale to the patients daily. The gender, age, comorbidity, treatments, intubation, and mortality rates of the patients were recorded. Multivariate analyses were performed by examining predisposing factors. arterial blood gases, hemograms, biochemistry, and brain magnetic resonance imaging. RESULTS: There were 64 patients in delirium clinic, 65.6% (n=42) of them were male. Hypokinetic delirium was more common in 60.9% (n=39). 79.4% of the patients who received ventilator support were male (p=0.013). When mortality was analyzed in this group, hypoactive delirium was found to be significantly higher (p=0.035). In addition, leukocyte levels were higher in patients with hypokinetic delirium (p=0.029). Ferritin and fibrinogen levels were higher in patients with hyperkinetic delirium (p=0.039, p=0.008, respectively). CONCLUSIONS: The presence of additional diseases such as advanced age, male gender, hypertension, coronary artery disease, dementia, and hypoxia were factors that increased the frequency of delirium. In addition, the mortality rate was higher in patients with hypokinetic delirium.en_US
dc.identifier.endpage4448en_US
dc.identifier.issn1128-3602
dc.identifier.issue12en_US
dc.identifier.pmid35776045en_US
dc.identifier.startpage4440en_US
dc.identifier.urihttps://hdl.handle.net/11616/102603
dc.identifier.volume26en_US
dc.identifier.wosWOS:000823313800004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCOVID-19en_US
dc.subjectPneumoniaen_US
dc.subjectDeliriumen_US
dc.subjectMortalityen_US
dc.titleClinical features and predisposing factors of delirium due to COVID-19 pneumonia in intensive care unitsen_US
dc.typeArticleen_US

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