The Effects on Oxidative Systems in Liver Tissues of Systemic Ozone Application after Critical Size Hone Defect Surgery in Rat Mandibles

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dc.authoridErdemli, Erman/0000-0003-4596-7525
dc.authorwosidAKGÜL, Hasan HA/C-6510-2016
dc.authorwosidErdemli, Erman/ABI-8193-2020
dc.contributor.authorErdemli, Mehmet Erman
dc.contributor.authorAkgul, Hasan
dc.contributor.authorSelamoglu, Zeliha
dc.date.accessioned2024-08-04T21:02:03Z
dc.date.available2024-08-04T21:02:03Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractExamination of the changes that non-toxic doses of antioxidant action ozone used in increasing osteogenic activity by dentists causes on rat liver tissues. The effects of ozone applications that are significant in mandibular bone defect therapies and oral and maxillofacial surgery practice on oxidant / antioxidant system in rat liver tissues are investigated by analyzing malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) parameters. While there were statistically significant reductions in MDA levels and SOD activities after 15 and 45 days long ozone applications on critical mandibular bone defect induced rat livers, statistically significant increases were observed in GSH levels and CAT activities (P <= 0.05). This is the first study where the effects of ozone therapies used in treatment of mandibular bone defect on liver tissue oxidant / antioxidant system in rats are scrutinized with the analysis of biochemical parameters. It was determined that ozone applications did not have any negative effects on liver tissue oxidant / antioxidant system and concurrently had positive effects on liver antioxidant system and to reveal the biochemical mechanism completely, further studies are needed.en_US
dc.identifier.doi10.25083/rbl/24.3/538.544
dc.identifier.endpage544en_US
dc.identifier.issn1224-5984
dc.identifier.issue3en_US
dc.identifier.startpage538en_US
dc.identifier.urihttps://doi.org/10.25083/rbl/24.3/538.544
dc.identifier.urihttps://hdl.handle.net/11616/104427
dc.identifier.volume24en_US
dc.identifier.wosWOS:000472746500023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherArs Docendien_US
dc.relation.ispartofRomanian Biotechnological Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiveren_US
dc.subjectmandibular bone defecten_US
dc.subjectoxidative stressen_US
dc.subjectozoneen_US
dc.subjectraten_US
dc.titleThe Effects on Oxidative Systems in Liver Tissues of Systemic Ozone Application after Critical Size Hone Defect Surgery in Rat Mandiblesen_US
dc.typeArticleen_US

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