Stenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing

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dc.authoridTanriverdi, Elif Seren/0000-0002-0449-0356
dc.authoridYashar, Meltem/0000-0003-4325-3430
dc.authoridBasarir, Kerem Edip/0000-0002-6954-9996
dc.authoridYILMAZ, Mesut/0000-0001-8022-7325
dc.authorwosidTanriverdi, Elif Seren/ABE-4472-2021
dc.authorwosidYilmaz, Mesut/KWU-0546-2024
dc.contributor.authorYashar, Meltem
dc.contributor.authorBasarir, Kerem E.
dc.contributor.authorTanriverdi, Elif S.
dc.contributor.authorCelep, Selcuk
dc.contributor.authorSirekbasan, Leyla
dc.contributor.authorRakici, Erva
dc.contributor.authorEjder, Nebahat
dc.date.accessioned2024-08-04T21:01:12Z
dc.date.available2024-08-04T21:01:12Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Nosocomial Stenotrophomonas maltophilia-related cases are rising and pose a threat to immunocompromised patients. Twelve patients from our pediatric intensive care unit (PICU) presented with S maltophilia-associated bloodstream infection. Methods: This outbreak investigation includes 12 patients from PICU between the ages of 2 months and 4 years (mean 16 months, 7 male). To identify the origin, samples from all possible sources throughout the hospital were collected and ran through DNA isolation and Pulse Field Gel Electrophoresis. Results: 120 samples were collected during the outbreak. 31 samples (26%) were positive for S maltophilia. 30 S maltophilia isolates were analyzed, 10 different genotypes were identified. Clustering isolates were grouped into 3 different clusters (tolerance and optimization 1.0, cutoff 90%). The largest cluster was genotype 1, which included 19 isolates, those belong to patients' samples and a sample from a pull -out faucet inside the PICU. The Pull -out faucet was the origin of the bloodstream infection. Discussion: Pull -out faucets allow biofilm production, due its structure. Pulse Field Gel Electrophoresis identifies the transmission dynamics of the outbreak, with its high discriminatory power. Conclusions: Water sources should be monitored on a regular basis. Pull -out faucets enable bacterial overgrowth; therefore, we recommend water surveillance during outbreak investigations. (c) 2023 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajic.2023.11.018
dc.identifier.endpage610en_US
dc.identifier.issn0196-6553
dc.identifier.issn1527-3296
dc.identifier.issue5en_US
dc.identifier.pmid38043636en_US
dc.identifier.startpage605en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajic.2023.11.018
dc.identifier.urihttps://hdl.handle.net/11616/104188
dc.identifier.volume52en_US
dc.identifier.wosWOS:001233915100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.ispartofAmerican Journal of Infection Controlen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStenotrophomonas maltophilia bacteremiaen_US
dc.subjectImmunocompromised Patientsen_US
dc.subjectFaucet aeratoren_US
dc.subjectGenotypeen_US
dc.subjectOutbreak-investigationen_US
dc.titleStenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typingen_US
dc.typeArticleen_US

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