Antiinflammatory and antioxidant activities of different hemostatics and pulp capping materials applied on rat teeth Biochemical effects of direct pulp capping with different hemostatics

Basit Öğe Kaydı
dc.authoriddemir, pınar/0000-0003-2030-5429
dc.authorwosiddemir, pınar/AAE-7027-2020
dc.contributor.authorSaygin, Aysegul Goze
dc.contributor.authorUnal, Murat
dc.contributor.authorErcan, Nazli
dc.contributor.authorDemir, Pinar
dc.date.accessioned2024-08-04T20:56:29Z
dc.date.available2024-08-04T20:56:29Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: This study aimed to investigate the anti-inflammatory and antioxidant activities of different hemostatic agents and pulp capping materials. Material and Methods: Ninety-six Wistar albino mate rats were divided into the following groups: Sterile Saline (SS), Sodium Hypochlorite (NaOCl), Mecsina Hemostopper (MIAS). Occlusal cavities were prepared in the first molar teeth. Hemostatic agents were used to control bleeding and different pulp capping materials were applied on the exposed pulp area. Subgroups were created according to pulp capping materials (Dycal, Biodentine Theracal, MTA RepairHP). Half of the groups were left to wait for sacrifice on the 7th day and the others on the 28th day. Cardiac blood was taken to determine of antiinflammatory and antioxidant serum markers. Results: The use of different hemostatic agents in terms of antioxidant (CAT, GPX) and anti-inflammatory (IL1-beta, TNF-alpha, IL-6) activity was statistically significant (p <0.05). There was no statistical significance between groups for SOD (p> 0.05). IL-6 was significantly higher on the 7th day than on the 28th day (p <0.05). The and-inflammatory activity reduced from the 7th to the 28th day, in contrast, antioxidant activity induced. Discussion: The inflammation process was related to the hemostatic agents and the capping materials used in DPC treatment. MHS may be an alternative for DPC treatment for bleeding control.en_US
dc.description.sponsorshipScientific Research Project Fund of Cumhuriyet University [DIS-220]; Mecsina Hemostooper(R) companyen_US
dc.description.sponsorshipThis work was supported by the Scientific Research Project Fund of Cumhuriyet University under project number DIS-220 and Mecsina Hemostooper (R) company.en_US
dc.identifier.doi10.4328/ACAM.20595
dc.identifier.endpage384en_US
dc.identifier.issn2667-663X
dc.identifier.startpage379en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20595
dc.identifier.urihttps://hdl.handle.net/11616/102370
dc.identifier.volume12en_US
dc.identifier.wosWOS:000731638200004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnti-Inflammatory Effecten_US
dc.subjectAntioxidantsen_US
dc.subjectDentistryen_US
dc.subjectDirect Pulp Cappingen_US
dc.subjectMecsina Hemostopperen_US
dc.titleAntiinflammatory and antioxidant activities of different hemostatics and pulp capping materials applied on rat teeth Biochemical effects of direct pulp capping with different hemostaticsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu