Galectin-1 as a potential diagnostic biomarker in polycystic ovary syndrome

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dc.contributor.authorAladag, H.
dc.contributor.authorKiran, T. R.
dc.contributor.authorInceoglu, F.
dc.contributor.authorYildirim, E.
dc.contributor.authorYaprak, B.
dc.contributor.authorKarabulut, A. B.
dc.contributor.authorAladag, M.
dc.date.accessioned2024-08-04T20:58:52Z
dc.date.available2024-08-04T20:58:52Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: This study was aimed at comparing the routine laboratory pa-rameters and Galectin-1 levels of control and polycystic ovarian syndrome patients.PATIENTS AND METHODS: 88 patients di-agnosed with polycystic ovary syndrome and 88 healthy controls were considered for the study. Age groups of the patients ranged from 18 to 40. Serum TSH, Beta HCG, glucose, insulin, HO-MA-IR, Hb1A1c, triglyceride, total cholesterol, LDL FSH, LH, E2, prolactin, testosterone, SHBG, DHESO4, HDL, Gal-1 levels were analyzed for each subject.RESULTS: FSH, LH, LH/FSH, E2, prolactin, testosterone, SHBG, DHESO4, HDL and Gal -1 values of the subjects included in the study were statistically significantly different between the groups (p<0.05). Gal-1 and DHESO4 showed a strong positive connection (p=0.05). The sen-sitivity of Gal-1 level in PCOS patients was cal-culated as 0.997 and specificity as 0.716.CONCLUSIONS: High levels of Gal-1 in PCOS patients suggest that it increases due to overex-pression in response to inflammation.en_US
dc.identifier.endpage2551en_US
dc.identifier.issn1128-3602
dc.identifier.issue6en_US
dc.identifier.pmid37013772en_US
dc.identifier.startpage2543en_US
dc.identifier.urihttps://hdl.handle.net/11616/103242
dc.identifier.volume27en_US
dc.identifier.wosWOS:000971936600039en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolycystic ovary syndromeen_US
dc.subjectGal-1en_US
dc.subjectDHESO4en_US
dc.subjectDiabe-tesen_US
dc.subjectInflammationen_US
dc.subjectObesityen_US
dc.titleGalectin-1 as a potential diagnostic biomarker in polycystic ovary syndromeen_US
dc.typeArticleen_US

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