Screening of blood donors for HCV RNA by RT-PCR
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Tarih
1996
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Genel ve Dahili Tıp
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info:eu-repo/semantics/openAccess
Özet
Öz:Toplam 376 donör kanı anti-HCV yönünden ELISA ile (ikinci jenerasyon) test edildi. 164 örnekte (%40.95) anti-HCV negatif iken 212 serumda (%59.05) anti-HCV pozitif bulundu. 76 serum (%20.21) da HCV RNA pozitif bulundu. Anti-HCV negatif serumların 6'sında (%3.65) HCV RNA pozitif bulundu. Bu sonuçlar HCV antikorlarını gösteren ikinci kuşak ELISA testleri ile viremi arasında korelasyon olduğunu gösterir, fakat düşük viremili HCV taşıyıcılarını tespit etmek için bu testler yeterince sensitif değildir. [Turgut Özal Tıp Merkezi Dergisi 1996;3(4):303-305]
Abstract:A total of 376 bood donors have been tested for anti-HCV by ELISA (second generation) test. 164 of 376 (40.95%) specimens were anti-HCV negative. 212 (59.05%) sera were anti-HCV positive^Seventy-six of total sera (20.21%) were found positive for HCV RNA. In 70 of 212 (33.01%) anti-HCV positive sera, HCV RNA was found positive. Six of 164 anti-HCV negative sera (3.65%) were considered positive for HCV RNA. These results indicate that reactivity in second generation assays for hepatitis C virus antibodies correlates with viremia, but they are not sensitive enough to screen hepatitis C virus carriers with low viremia. [Journal of Turgut Özal MedicalCenter 1996;3(4):303-305]
Abstract:A total of 376 bood donors have been tested for anti-HCV by ELISA (second generation) test. 164 of 376 (40.95%) specimens were anti-HCV negative. 212 (59.05%) sera were anti-HCV positive^Seventy-six of total sera (20.21%) were found positive for HCV RNA. In 70 of 212 (33.01%) anti-HCV positive sera, HCV RNA was found positive. Six of 164 anti-HCV negative sera (3.65%) were considered positive for HCV RNA. These results indicate that reactivity in second generation assays for hepatitis C virus antibodies correlates with viremia, but they are not sensitive enough to screen hepatitis C virus carriers with low viremia. [Journal of Turgut Özal MedicalCenter 1996;3(4):303-305]
Açıklama
Yıl: 1996Cilt: 3Sayı: 4ISSN: 1300-1744Sayfa Aralığı: 303 - 305Metin Dili:İngilizce
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Genel ve Dahili Tıp
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Künye
SÖNMEZ E,TROISI C,HOLLINGER F. B,LIN H. J,NAEM M (1996). Screening of blood donors for HCV RNA by RT-PCR. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 3(4), 303 - 305.
