Hepatic artery thrombosis related risk factors after living donor liver transplantation single center experience from Turkey

dc.authorid116537en_US
dc.contributor.authorÜnal, Bülent
dc.contributor.authorGönültaş, Fatih
dc.contributor.authorAydın, Cemalettin
dc.contributor.authorOtan, Emrah
dc.contributor.authorKayaalp, Cüneyt
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2017-08-11T08:25:13Z
dc.date.available2017-08-11T08:25:13Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim. The purpose of this retrospective study is to evaluate the risk factors hepatic artery thrombosis (HAT) after orthotopic liver transplantation (OLT) in a consecutive series from a single center. Materials and Methods. Between January 2010 and May 2012, we performed 278 living donor liver transplantations, including 189 males and 89 females. We compared the risk factors between HAT and non-HAT groups according to the following variables: age, gender, body mass index (BMI), graft weight, use of graft, Child-Pugh and model for end stage liver disease score, level of hemoglobin, blood pressure, operation time, blood transfusion, presence of ascites, international normalized ratio (INR) level, and etiology. Results. Eighteen patients, including 15 males and 3 female, had HAT after the operation (mean age, 45.1 years; age range, 22–60 years). There were no pediatric patients in the HAT group. HAT rate was 6.5% in our series. Graft loss and retransplantation due to HAT was 38.7% in a 2-year period. Biliary leakage was observed in 72 (25.8%) living donor liver transplantations; this rate was higher in patients with HAT (n 8; 44.4%). The infection rate was 50% (n 9) in the HAT group and was 32.7% (n 91) in the non-HAT group. Mean INR value was 2.15 in the HAT group and 1.72 in the non-HAT group. When we compared the groups according to use of graft for anastomosis, biliary lekage, infection, and INR value, the differences were statistically significant (P .05). Conclusion. Although the results of OLT have improved over the past years, HAT is still associated with substantial morbidity, high incidence of graft failure, and high mortality rates. The most important findings associated with HAT in our series were found as INR levels, bile leakage, and resistant infections. Use of vascular graft for hepatic artery anastomosis was found to increase HAT risk.en_US
dc.identifier.citationÜnal, B. Gönültaş, F. Aydın, C. Otan, E. Kayaalp, C. Yılmaz, S. (2013). Hepatic artery thrombosis related risk factors after living donor liver transplantation single center experience from Turkey. Transplantation Proceedings. 45(3), 974–977.en_US
dc.identifier.doi10.1016/j.transproceed.2013.02.070en_US
dc.identifier.endpage977en_US
dc.identifier.issn00411345
dc.identifier.issue3en_US
dc.identifier.startpage974en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0041134513002595
dc.identifier.urihttps://hdl.handle.net/11616/7551
dc.identifier.volume45en_US
dc.language.isoenen_US
dc.publisherTransplantation Proceedingsen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleHepatic artery thrombosis related risk factors after living donor liver transplantation single center experience from Turkeyen_US
dc.typeArticleen_US

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