Outcomes of surgery for gallbladder cancer A single-center experience

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dc.authoridKaradag Soylu, Nese/0000-0002-6303-5484
dc.authoridSAHIN, TEVFIK TOLGA/0000-0002-9132-6115
dc.authoridBASKIRAN, ADIL/0000-0002-7536-1631
dc.authoridÖzgör, Dinçer/0000-0001-8519-8869;
dc.authorwosidKaradag Soylu, Nese/ABH-9544-2020
dc.authorwosidsahin, emrah/B-8806-2019
dc.authorwosidSAHIN, TEVFIK TOLGA/AAA-9648-2021
dc.authorwosidBASKIRAN, ADIL/ABI-2356-2020
dc.authorwosidÖzgör, Dinçer/AAB-3523-2021
dc.authorwosidBarut, Bora/ABD-9882-2020
dc.contributor.authorBaskiran, Adil
dc.contributor.authorSahin, Emrah
dc.contributor.authorKaradag, Nese
dc.contributor.authorSahin, Tevfik Tolga
dc.contributor.authorBarut, Bora
dc.contributor.authorOzgor, Dincer
dc.contributor.authorDirican, Abuzer
dc.date.accessioned2024-08-04T21:00:08Z
dc.date.available2024-08-04T21:00:08Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: Gallbladder cancer (GBC) is a rare clinical entity that has a poor prognosis. Radical resection with meticulous lymph node dissection is the only treatment option. The aim of the present study is to evaluate the efficacy of radical resection for GBC in the early postoperative period with the viewpoint of clinicopathological correlation. METHODS: Patients (n=24) who underwent radical resection with lymph node dissection for GBC between 2015 and 2017 were included. Demographic data, histopathologic tumor type, preoperative tumor markers, pathologic tumor size/stage (depth of invasion), lymph node metastasis and metastasis rates, and postoperative early mortality were evaluated. The patients were grouped in two groups according to lymph node metastases: Group 1 (without lymph node metastasis) and Group 2 (with lymph node metastasis). RESULTS: The median age of the patients in Group 1 and Group 2 was 65 (range, 42-89) years and 68 (range, 48-87) years, respectively (p>0.05). The female/male ratio in Group 1 and Group 2 was 4/4 and 13/3, respectively (p>0.05). There was a tendency for increased metastasis in Group 2 compared with Group 1 (31% vs. 0%) (p>0.05). Also, 88% of the tumors in Group 2 were in the advanced stage, whereas the rate was 37% in Group 1 (p<0.05). There was early postoperative mortality in seven patients who underwent resection. Four of the seven patients (43%) were from Group 2 and three (37%) from Group 1 (p>0.05). CONCLUSION: Lymph node metastasis in GBC indicates advanced tumor stage. This causes a more complex surgical resection and therefore results in higher early postoperative mortality.en_US
dc.identifier.doi10.14744/ncl.2017.69320
dc.identifier.endpage198en_US
dc.identifier.issn2148-4902
dc.identifier.issue3en_US
dc.identifier.pmid30688940en_US
dc.identifier.startpage195en_US
dc.identifier.urihttps://doi.org/10.14744/ncl.2017.69320
dc.identifier.urihttps://hdl.handle.net/11616/103820
dc.identifier.volume5en_US
dc.identifier.wosWOS:000445820800004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofNorthern Clinics of Istanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGallbladder canceren_US
dc.subjectradical resectionen_US
dc.subjectlymph node dissectionen_US
dc.subjectlymph node metastasisen_US
dc.subjectextra hepatic biliary tree resectionen_US
dc.titleOutcomes of surgery for gallbladder cancer A single-center experienceen_US
dc.typeArticleen_US

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