Familial Mediterranean Fever in a Patient with PFAPA Syndrome
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Yayincilik
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome is one of the recurrent fever syndrome in childhood. Headache, abdominal pain, and joint pain can be seen in some patients, in addition to the classical signs. PFAPA attacks resolve with prednisolone. Membranous tonsillitis, lymphadenopathy, and occasionally aphthae were detected during each episode in a patient presenting with high fever, about 12 times until four years of age. All attacks were resolved completely with single-dose prednisolone in the patient, who was diagnosed with PFAPA syndrome. Genetic analysis was requested because of abdominal pain that was occasionally observed during attacks. Heterozygous mutation of M694V was detected through genetic investigation, and colchicine was initiated. The patient was diagnosed with familial Mediterranean fever (FMF) due to resolved abdominal pain and recurrent fever after colchicine therapy. It is known that some FMF patients benefit from prednisolone therapy. Therefore, other periodic fever syndromes should be excluded before the diagnosis of PFAPA and FMF should be considered in patients with PFAPA syndrome complaining of recurrent abdominal pain.
Açıklama
Anahtar Kelimeler
Abdominal pain, familial Mediterranean fever, PFAPA, prednisolone
Kaynak
Journal of Pediatric Research
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
2
Sayı
2
