The Rates of Seropositivity and Seroconversion of Toxoplasma Infection in Pregnant Women

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dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X;
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidkaraoğlu, leyla/JQP-1016-2023
dc.authorwosiddogan, keziban/HCI-2278-2022
dc.contributor.authorDogan, Keziban
dc.contributor.authorKafkasli, Ayse
dc.contributor.authorKaraman, Ulku
dc.contributor.authorAtambay, Metin
dc.contributor.authorKaraoglu, Leyla
dc.contributor.authorColak, Cemil
dc.date.accessioned2024-08-04T21:02:09Z
dc.date.available2024-08-04T21:02:09Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractInfections caused by Toxoplasma gondii are frequently asymptomatic in healthy adults, however they may be serious in pregnant women and immunocompromised patients. The aims of this study were to investigate the rates of seropositivity and seroconversion in pregnant women and newborn cord blood samples, and to evaluate those data in the view of relation to lifestyle and nutrition. A total of 312 pregnant women (mean age: 28.1 +/- 5.2 years) who were admitted to and followed by gynecology clinics of Inonu University Medical School Hospital, Malatya, Turkey were included in this observational and cross-sectional study. Anti-toxoplasma IgG and IgM antibodies in pregnants and newborn cord sera were screened by commercial ELISA and immunofluorescence antibody (BioTek; USA) methods. A total of 312 sera from pregnant women and 312 cord blood samples during delivery were collected. IgG seropositivity rate in pregnants was found as 37.5% (117/312), seroconversion was not determined in restrained pregnants and T.gondii IgM was found negative in all pregnants. Also in all newborns IgM was negative and IgG seropositivity was determined as 33.3% (104/312) in cord blood. There was a statistically significant relationship between IgG seropositivity and raw meat consumption (p<0.001) and being engaged in agriculture (p<0.005). It was concluded that toxoplasma antibodies should routinely be searched on the first visit of the pregnants and the seronegative cases should be trained about the preventive measures related to toxoplasmosis. The follow-up of toxoplasma seronegative cases during pregnancy can be achieved by only detecting the IgM class antibodies and this will also reduce the cost of screen test.en_US
dc.identifier.endpage294en_US
dc.identifier.issn0374-9096
dc.identifier.issue2en_US
dc.identifier.pmid22639318en_US
dc.identifier.startpage290en_US
dc.identifier.urihttps://hdl.handle.net/11616/104517
dc.identifier.volume46en_US
dc.identifier.wosWOS:000303952800014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherAnkara Microbiology Socen_US
dc.relation.ispartofMikrobiyoloji Bultenien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectToxoplasma gondiien_US
dc.subjectseropositivityen_US
dc.subjectpregnancyen_US
dc.subjectnewbornen_US
dc.titleThe Rates of Seropositivity and Seroconversion of Toxoplasma Infection in Pregnant Womenen_US
dc.typeArticleen_US

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