Management of thrombosis in a pediatric renal transplant patient with factor VII deficiency A dilemma concerning recombinant factor VIIa
Küçük Resim Yok
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Athens Medical Soc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Hemorrhagic complications in surgical patients with congenital factor VII deficiency are a major concern. Replacement therapy is required, in which recombinant factor VIIa is the first treatment choice, by virtue of its higher efficacy and no risk of infection. Because of the risk of vascular thrombosis, recombinant factor VIIa treatment may result in catastrophic outcomes, including graft loss in transplant patients. We present the case of a 7-year-old male who underwent renal transplantation and who developed renal thrombosis after recombinant factor VIIa substution therapy for factor VII deficiency.
Açıklama
Anahtar Kelimeler
Factor VII deficiency, Pediatric renal transplantation, Recombinant factor VIIa, Renal transplantation, Thrombosis
Kaynak
Archives of Hellenic Medicine
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
37
Sayı
3