Management of thrombosis in a pediatric renal transplant patient with factor VII deficiency A dilemma concerning recombinant factor VIIa

Küçük Resim Yok

Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Athens Medical Soc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Hemorrhagic complications in surgical patients with congenital factor VII deficiency are a major concern. Replacement therapy is required, in which recombinant factor VIIa is the first treatment choice, by virtue of its higher efficacy and no risk of infection. Because of the risk of vascular thrombosis, recombinant factor VIIa treatment may result in catastrophic outcomes, including graft loss in transplant patients. We present the case of a 7-year-old male who underwent renal transplantation and who developed renal thrombosis after recombinant factor VIIa substution therapy for factor VII deficiency.

Açıklama

Anahtar Kelimeler

Factor VII deficiency, Pediatric renal transplantation, Recombinant factor VIIa, Renal transplantation, Thrombosis

Kaynak

Archives of Hellenic Medicine

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

37

Sayı

3

Künye