Roles of ATR1 paralogs YMR279c and YOR378w in boron stress tolerance

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dc.authorid130618en_US
dc.authorid115517en_US
dc.authorid24898en_US
dc.authorid110769en_US
dc.contributor.authorBozdağ, Gönensin Ozan
dc.contributor.authorUluışık, İrem
dc.contributor.authorGülce, Sıla Gülcüler
dc.contributor.authorKarakaya, Hüseyin Çağlar
dc.contributor.authorKoç, Ahmet
dc.date.accessioned2017-06-11T08:34:45Z
dc.date.available2017-06-11T08:34:45Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.descriptionBiochemical and Biophysical Research Communicationsen_US
dc.description.abstractBoron is a necessary nutrient for plants and animals, however excess of it causes toxicity. Previously, Atr1 and Arabidopsis Bor1 homolog were identified as the boron efflux pump in yeast, which lower the cytosolic boron concentration and help cells to survive in the presence of toxic amount of boron. In this study, we analyzed ATR1 paralogs, YMR279c and YOR378w, to understand whether they participate in boron stress tolerance in yeast. Even though these genes share homology with ATR1, neither their deletion rendered cells boron sensitive nor their expression was significantly upregulated by boron treatment. However, expression of YMR279, but not YOR378w, from the constitutive GAPDH promoter on a high copy plasmid provided remarkable boron resistance by decreasing intracellular boron levels. Thus our results suggest the presence of a third boron exporter, YMR279c, which functions similar to ATR1 and provides boron resistance in yeast.en_US
dc.identifier.citationBozdag, G. O., ULUIŞIK, İ., GÜLCE, G., KARAKAYA, H. Ç., & KOÇ, A. (2011). Roles Of ATR1 Paralogs YMR279c And YOR378w İn Boron Stress Tolerance. Biochemical And Biophysical Research Communications, 409(4), 748–751.en_US
dc.identifier.doi10.1016/j.bbrc.2011.05.080en_US
dc.identifier.endpage751en_US
dc.identifier.issue4en_US
dc.identifier.startpage748en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0006291X11008473
dc.identifier.urihttps://hdl.handle.net/11616/7081
dc.identifier.volume409en_US
dc.language.isoenen_US
dc.publisherBiochemical and Biophysical Research Communicationsen_US
dc.relation.ispartofBiochemical and Biophysical Research Communicationsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBoronen_US
dc.subjectBoric aciden_US
dc.subjectYeasten_US
dc.subjectStress responseen_US
dc.subjectATR1en_US
dc.subjectYmr279cen_US
dc.titleRoles of ATR1 paralogs YMR279c and YOR378w in boron stress toleranceen_US
dc.typeArticleen_US

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