The circulating alarin level was elevated in infertile women with poor ovarian reserve

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dc.authoridYıldırım, Engin/0000-0001-7937-4141
dc.authoridGORKEM, Umit/0000-0002-0848-9731
dc.authorwosidYıldırım, Engin/AAZ-2330-2021
dc.authorwosidGörkem, Ümit/ABG-8361-2021
dc.contributor.authorYildirim, Engin
dc.contributor.authorGorkem, Umit
dc.date.accessioned2024-08-04T21:01:22Z
dc.date.available2024-08-04T21:01:22Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective We aimed to reveal the association of serum alarin level with POR status of the infertile women in the present study. Methods The eligibility criteria for this prospective cross-sectional study included a total of 92 infertile women attending the Hitit University Hospital, and all participant women were categorized into two main groups of ovarian reserve: (i) Poor ovarian reserve (POR) group (n = 40) based on ESHRE consensus and (ii) Control group (NOR) (n = 52). Results The mean adjusted-ages and BMI values of the NOR and POR groups were statistically comparable (p = .057 and p = .600, respectively). The mean E2, FSH, and LH levels were elevated in the POR group (p < .001, for all). The mean AFC and AMH concentration were significantly reduced in the POR group (p < .001, for both). In addition, there was a significant increase in the serum alarin level in the POR group (p < .001). Pearson's analysis revealed that the mean BMI value of the POR group had a weak and negative correlation (r = 0.318, p = .046). Also, there was no correlation between serum alarin with E2 and FSH levels in both study groups. A weak and positive correlation was found between serum alarin and LH concentration only in the POR group (r = 0.318, p = .045). The mean AMH and AFC values were not significantly correlated with serum alarin levels. Conclusion The circulating alarin level was significantly elevated in infertile women with POR patterns. In addition, the alarin level was significantly correlated with the serum LH concentration in the POR pattern.en_US
dc.description.sponsorshipScientific Research Unit of the Hitit University, Corum, Turkeyen_US
dc.description.sponsorshipThis research was supported by The Scientific Research Unit of the Hitit University, Corum, Turkey.en_US
dc.identifier.doi10.1080/09513590.2021.1950683
dc.identifier.endpage1131en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue12en_US
dc.identifier.pmid34241554en_US
dc.identifier.startpage1128en_US
dc.identifier.urihttps://doi.org/10.1080/09513590.2021.1950683
dc.identifier.urihttps://hdl.handle.net/11616/104296
dc.identifier.volume37en_US
dc.identifier.wosWOS:000671486700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlarinen_US
dc.subjectluteinizing hormoneen_US
dc.subjectpoor ovarian reserveen_US
dc.subjectnormal ovarian reserveen_US
dc.titleThe circulating alarin level was elevated in infertile women with poor ovarian reserveen_US
dc.typeArticleen_US

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