Corneal endothelial changes in patients with vitamin D deficiency

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dc.contributor.authorÇankaya, Cem
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorGündüz, Abuzer
dc.date.accessioned2019-07-11T07:47:00Z
dc.date.available2019-07-11T07:47:00Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study is to evaluate the effect of vitamin D deficiency on corneal endothelial layer using specular microscopy. Methods: Fifty-eight eyes of 58 patients whose vitamin 13 level was below 15 ng/ml and who had no ocular pathology were included in the study (Group 1). Forty eyes of 40 age-and sex-matched subjects were enrolled as control group (Group 2). Corneal endothelial cell density (CD), coefficient of variation (CV), hexagonal cell ratio (HEX), and central corneal thickness (CCT) were measured using specular microscopy (Konan Medical Inc., Nishinomiya, Japan). The obtained data were compared between the groups. Results: There was no significant difference between the groups in terms of age and gender (P = 0.344, P = 0.399, respectively). The mean CD value was 2772.79 +/- 202.21 cells/mm(2) in Group 1 and 2954.97 +/- 116.89 cells/mm(2) in Group 2 (P = 0.001). The mean CV value was 30.31 +/- 3.65 in Group 1 and 28.20 +/- 2.71 in Group 2 (P = 0.003). The mean HEX value was 46.56 +/- 6.32 in Group 1 and 51.07 +/- 5.28 in Group 2 (P = 0.001). The mean CCT value was 555.87 +/- 36.90 mu in group 1 and 549.0 +/- 37.39 mu in Group 2 (P = 0.96). Conclusion: Vitamin D deficiency may affect the corneal endothelial layer. Patients with vitamin D deficiency should be evaluated for endothelial parameters in particular before an intraocular surgery. Further studies are needed to confirm our results.en_US
dc.identifier.citationÇankaya, C. Cumurcu, T. Gündüz, A. (2018). Corneal endothelial changes in patients with vitamin D deficiency. Cilt:66 Sayı:9, 1256-1261 ss.en_US
dc.identifier.doi10.4103/ijo.IJO_238_18en_US
dc.identifier.endpage1261en_US
dc.identifier.issue9en_US
dc.identifier.startpage1256en_US
dc.identifier.urihttps://hdl.handle.net/11616/12518
dc.identifier.volume66en_US
dc.language.isoenen_US
dc.publisherWOLTERS KLUWER MEDKNOW PUBLICATIONS, WOLTERS KLUWER INDIA PVT LTD , A-202, 2ND FLR, QUBE, C T S NO 1498A-2 VILLAGE MAROL, ANDHERI EAST, MUMBAI, 400059, INDIAen_US
dc.relation.ispartofIndıan journal of ophthalmologyen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectOxıdatıve Stress Markersen_US
dc.subjectMembrane Calcıum-Pumpen_US
dc.subjectChronıc-Renal-Faılureen_US
dc.subjectSpecular Mıcroscopyen_US
dc.subjectCalcıtrıol Receptoren_US
dc.subjectAnterıor Uveıtısen_US
dc.subjectEyeen_US
dc.subjectDıseaseen_US
dc.subjectBarrıeren_US
dc.subjectCellsen_US
dc.titleCorneal endothelial changes in patients with vitamin D deficiencyen_US
dc.typeArticleen_US

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