Fulminant hepatitis A infection in second trimester of pregnancy requiring living donor liver transplantation
Yükleniyor...
Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Journal of Obstetrics and Gynaecology Research
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We present an 18-year-old pregnant woman who was referred to our emergency clinic as a case of acute hepatic
failure and hepatic encephalopathy. Laboratory tests showed abnormal liver function tests and serological
workup was consistent with acute hepatitis A infection. Ultrasonography revealed a single live fetus with fetal
biometry compatible with 18 gestational weeks. The patient underwent a highly urgent liver transplantation
using a right lobe graft from her husband. Histological examination of the explanted liver showed acute,
lymphocyte-rich, diffuse necrotizing hepatitis, consistent with acute necrotizing hepatitis A. After the operation
her allograft function gradually recovered. Her follow-up obstetrics ultrasound revealed a male fetus with
severely decreased amniotic fluid. The patient was informed about the poor prognosis of her pregnancy and
the pregnancy was terminated by vaginal misoprostol induction. She has maintained a good general condition
and liver function for 4 months postoperatively, up to the present time.
Açıklama
Anahtar Kelimeler
Hepatic encephalopathy, Hepatic failure, Hepatitis A, Liver transplantation, Pregnancy
Kaynak
Journal of Obstetrics and Gynaecology Research
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
Künye
Şimşek, Ö. Y. Işık, B. Karaer, A. Çelik, Ö. Kutlu, R. Aydın, N. E. Yılmaz, S. (2012). Fulminant hepatitis A infection in second trimester of pregnancy requiring living donor liver transplantation. Journal of Obstetrics and Gynaecology Research. 4: 745–748.
