Diffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Disease

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dc.authoridKutlu, Ramazan/0000-0001-7941-7025
dc.authoridErdem, Gülnur/0000-0003-2200-8620
dc.authoridKahraman, Aysegul Sagir/0000-0002-2147-1181
dc.authoridKutlu, Ramazan/0000-0001-7941-7025
dc.authorwosidKutlu, Ramazan/B-1624-2016
dc.authorwosidErdem, Gülnur/GPS-7725-2022
dc.authorwosidKahraman, Aysegul Sagir/S-1526-2016
dc.authorwosidKutlu, Ramazan/AAE-5219-2020
dc.contributor.authorKalayci, Tugce Ozlem
dc.contributor.authorErdem, Gulnur
dc.contributor.authorKutlu, Ramazan
dc.contributor.authorKahraman, Aysegul
dc.contributor.authorAlkan, Alpay
dc.date.accessioned2024-08-04T20:57:41Z
dc.date.available2024-08-04T20:57:41Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA 46-year-old woman with Gaucher's disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted MRI (DW-MRI) and magnetic resonance spectroscopy (MRS) were performed to liver parenchyma and splenic nodules. MRS revealed lactate, lipid, acetate, and alanine peaks in splenic nodules, and choline, creatine, lipid, myo-inositolglycine, and lactate peaks in the liver parenchyma. The DW-MRI showed diffusion restriction in splenic nodules. It was concluded that MRI is a reliable method for the diagnosis and follow up of GD. Coupling DW-MRI and MRS allows quantitative evaluation, thereby increasing the efficacy of the method. This is the first report in the literature presenting advanced abdominal MRI findings in GD.en_US
dc.identifier.endpage93en_US
dc.identifier.issn1394-195X
dc.identifier.issn2180-4303
dc.identifier.issue3en_US
dc.identifier.pmid25246842en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://hdl.handle.net/11616/102841
dc.identifier.volume21en_US
dc.identifier.wosWOS:000420513000013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUniv Sains Malaysia, Sch Medical Sciencesen_US
dc.relation.ispartofMalaysian Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdiffusion magnetic resonance imagingen_US
dc.subjectGaucher diseaseen_US
dc.subjectmagnetic resonance spectroscopyen_US
dc.titleDiffusion-Weighted Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy Features of Abdominal Viscera in a Patient with Gaucher's Diseaseen_US
dc.typeArticleen_US

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