The influence of cigarette smoke on the epithelium of the vestibule

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dc.authoridEşrefoğlu, Mukaddes/0000-0003-3380-1480
dc.authorwosidEşrefoğlu, Mukaddes/JWA-4590-2024
dc.contributor.authorEsrefoglu, M
dc.contributor.authorSelimoglu, E
dc.contributor.authorEsrefoglu, M
dc.contributor.authorVuraler, Ö
dc.date.accessioned2024-08-04T21:02:05Z
dc.date.available2024-08-04T21:02:05Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIt is known that cigarette smoke induces cytological alterations on the respiratory and olfactory mucosa of the nasal cavity. We evaluated whether cigarette smoking had adverse effects on the epithelium of the vestibule, in the absence of any published ultrasutructural studies. We evaluated ten patients suffering from septum deviation, eight of whom were long-term smokers. While each layer of the epithelium obtained from the non-smokers consisted of a homogeneous cell population, each from the long-term smokers consisted of a heterogeneous cell population. The most prominent changes occurred in the shape and size of the cells and nuclei, the number and length of the cytoplasmic projections, the number and distribution pattern of the desmosomes, and the width of the intercellular spaces. We concluded that cigarette smoke produces hyperplastic and dysplastic changes, important factors related with cancer development, on the epithelium of the vestibule.en_US
dc.identifier.endpage709en_US
dc.identifier.issn0513-5796
dc.identifier.issue4en_US
dc.identifier.pmid12950128en_US
dc.identifier.startpage703en_US
dc.identifier.urihttps://hdl.handle.net/11616/104469
dc.identifier.volume44en_US
dc.identifier.wosWOS:000185292900020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherYonsei Univ College Medicineen_US
dc.relation.ispartofYonsei Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcigarette smokeen_US
dc.subjectvestibuleen_US
dc.subjectelectron microscopyen_US
dc.titleThe influence of cigarette smoke on the epithelium of the vestibuleen_US
dc.typeArticleen_US

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