Autonomic nervous system involvement in Behcet's disease -: A pupillometric study

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dc.authoridBayramlar, Huseyin/0000-0002-8118-1151
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authorwosidBayramlar, Huseyin/I-5876-2013
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.contributor.authorBayramlar, H
dc.contributor.authorHepsen, IF
dc.contributor.authorUguralp, M
dc.contributor.authorBölük, A
dc.contributor.authorÖzcan, C
dc.date.accessioned2024-08-04T20:57:13Z
dc.date.available2024-08-04T20:57:13Z
dc.date.issued1998
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to elucidate whether autonomic nervous system dysfunction exists in patients with Behcet's disease by pupillometric tests. Thirty-one patients with Behcet's disease with a mean age of 41.3 years (range 21-64) and 41 control subjects with a mean age of 39.5 years (range 18-66) were selected for the study. To test the autonomic nervous system, four pupillometric techniques were used: pupil cycle time (PCT), dark-adapted pupil size (DAPS), 0.05% pilocarpine drop test, and 1% phenylephrine drop test. In all four tests, there were significant differences between the patients and controls. Mean PCTs were 1,156 ms (range 856-1,560 ms) and 919 ms (range 650-1,261 ms) in the patients and controls, respectively (p < 0.0001). The mean DAPS was 0.45 (range 0.31-0.66) in the patients, whereas it was 0.56 (range 0.42-0.67) in controls (p < 0.001). Iris sensitivity to both 0.05% pilocarpine and 1% phenylephrine showed significant differences between patients and controls, respectively (p < 0.05, p < 0.05). Among all four tests, only 0.05% pilocarpine sensitivity was correlated with the duration of Behcet's disease (p < 0.05). The results suggest that the autonomic nervous system innervating the iris is affected in Behcet's disease. This involvement may be due to the vasculitic nature of Behcet's disease.en_US
dc.identifier.endpage186en_US
dc.identifier.issn1070-8022
dc.identifier.issue3en_US
dc.identifier.pmid9736202en_US
dc.identifier.startpage182en_US
dc.identifier.urihttps://hdl.handle.net/11616/102449
dc.identifier.volume18en_US
dc.identifier.wosWOS:000086626300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal of Neuro-Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautonomic nervous functionen_US
dc.subjectBehcer's diseaseen_US
dc.subjectpupilen_US
dc.subjectpupillometryen_US
dc.titleAutonomic nervous system involvement in Behcet's disease -: A pupillometric studyen_US
dc.typeArticleen_US

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