Relationship Between Viral Load and Laboratory Values and Radiological Findings in Patients with COVID-19

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dc.authoridAkçiçek, Mehmet/0000-0002-0232-1284
dc.authoridAydin, Sukru/0000-0003-1105-3338
dc.authorwosidAkçiçek, Mehmet/GLN-7854-2022
dc.authorwosidAydin, Sukru/AAM-3613-2021
dc.contributor.authorAltintop Geckil, Aysegul
dc.contributor.authorBenk, Isilay Gokce
dc.contributor.authorAydin, Sukru
dc.contributor.authorAkcicek, Mehmet
dc.date.accessioned2024-08-04T21:01:01Z
dc.date.available2024-08-04T21:01:01Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: This study investigates the relationship between the viral load calculated from oropharyngeal/nasopharyngeal swabs at diagnosis and the laboratory parameters and radiological findings in patients with Coronavirus disease-2019 (COVID-19). Materials and Methods: Sixty-seven patients who were positive for severe acute respiratory syndrome-coronavirus-2 via quantitative reverse transcription-polymerase chain reaction (qPCR) from their oropharyngeal/nasopharyngeal swabs and admitted to Malatya Turgut Ozal University Hospital were included in the study. Demographic data, laboratory parameters, and the severity of thorax computed tomography findings were recorded. The relationship between the viral load and these data was compared. Results: The mean age of the patients was 63.4 +/- 9.8 years, mean body mass index (BMI) was 28.6 +/- 5.4 kg/m(2), and mean cycle threshold (Ct) values were 21.4 +/- 5.2 cycles. No correlation was found between Ct value and gender, age, and BMI. There was a significant relationship between radiological severity and Ct value, age, and gender. There was a significant correlation between the Ct value and C-reactive protein, leukocyte, neutrophil, lymphocyte, neutrophil-lymphocyte ratio, ferritin, albumin, and calcium levels. In contrast, no significant correlation was found between hemoglobin, hematocrit, thrombocyte, urea, creatinine, total protein, gamma glutamyl transferase, alkaline phosphatase, sodium, potassium, D-dimer, procalcitonin levels, and Ct value. Conclusion: The viral load amount shown by PCR during the early period predicts the condition of the patient's lung in the advanced immunological phase. The Ct value can be an independent factor for evaluating the patient's radiological and biochemical status.en_US
dc.identifier.doi10.4274/mjima.galenos.2022.2022.26
dc.identifier.issn2147-673X
dc.identifier.urihttps://doi.org/10.4274/mjima.galenos.2022.2022.26
dc.identifier.urihttps://hdl.handle.net/11616/104012
dc.identifier.volume11en_US
dc.identifier.wosWOS:000964556200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofMediterranean Journal of Infection Microbes and Antimicrobialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSARS-CoV-2en_US
dc.subjectviral loaden_US
dc.subjectlymphopeniaen_US
dc.titleRelationship Between Viral Load and Laboratory Values and Radiological Findings in Patients with COVID-19en_US
dc.typeArticleen_US

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