Evaluation of factors associated with time to diabetic ketoacidosis resolution in children

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dc.authoridTekin, Mehmet/0000-0002-1157-1314
dc.authorwosidTekin, Mehmet/ABG-8307-2020
dc.contributor.authorOztekin, Mehmet
dc.contributor.authorKonca, Capan
dc.contributor.authorTekin, Mehmet
dc.contributor.authorBolu, Semih
dc.date.accessioned2024-08-04T20:58:44Z
dc.date.available2024-08-04T20:58:44Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: In this study, it was aimed to examine the relationship between clinical, demographic, and laboratory characteristics of patients at admission and time to diabetic ketoacidosis (DKA) resolution. Material and Methods: The files of patients with the diagnosis of DKA between January 2013 and December 2018 were reviewed retrospectively.Results: A total of 25 patients were included in the study. The mean age of the patients was 9.3 +/- 3.41 years. In 19 patients (76%), diabetes mellitus (DM) was diagnosed simultaneously with DKA. The mean time to DKA resolution was found to be significantly longer among patients with a family history of DM, newly diagnosed DM, respiratory distress, odor of acetone on the breath, altered consciousness, and severe coma. There was a significant correlation between the time to DKA resolution and the Pediatric Risk of Mortality score and the length of stay. There was also a significant negative correlation between time to DKA resolution and both pH and HCO3 levels. Discussion: DKA is an acute, severe, and life-threatening complication of type 1 DM in children. It is important to identify the factors affecting the prognosis and resolution time of comas in these patients in order to predict outcomes. Our findings show that the prognosis will be worse and the time to resolution will be longer among children with altered consciousness, newly diagnosed DM, respiratory distress, a high PRISM score, severe DKA coma, and severe acidosis at the time of admission.en_US
dc.identifier.doi10.4328/ACAM.21164
dc.identifier.endpage972en_US
dc.identifier.issn2667-663X
dc.identifier.issue9en_US
dc.identifier.startpage968en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.21164
dc.identifier.urihttps://hdl.handle.net/11616/103112
dc.identifier.volume13en_US
dc.identifier.wosWOS:000863271700006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChildrenen_US
dc.subjectComaen_US
dc.subjectDiabetic Ketoacidosis (DKA)en_US
dc.subjectFactorsen_US
dc.subjectPediatricen_US
dc.subjectResolution Timeen_US
dc.titleEvaluation of factors associated with time to diabetic ketoacidosis resolution in childrenen_US
dc.typeArticleen_US

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