Quality of life and related variables in patients with ankylosing spondylitis

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dc.authoridKarkucak, Murat/0000-0002-4348-8398
dc.authoridDuruöz, Mehmet Tuncay/0000-0003-3584-2788
dc.authoridKOZANOGLU, ERKAN/0000-0002-0167-3384
dc.authoridolmez, nese/0000-0002-9755-5875
dc.authoridBüyükavcı, Raikan Soydemir/0000-0002-2234-7158
dc.authoridSivrioglu, Koncuy/0000-0002-4296-9480
dc.authoridAtaman, Sebnem/0000-0003-3570-3825
dc.authorwosidKarkucak, Murat/B-6602-2016
dc.authorwosidTAN, FATMA AYSEN AKINCI/I-9210-2013
dc.authorwosidSoy, derya nazlı/JYP-8948-2024
dc.authorwosidDuruöz, Mehmet Tuncay/I-2307-2016
dc.authorwosidSivrioglu, Koncuy/AAG-8211-2021
dc.authorwosidAltan, Lale/AAH-1652-2021
dc.authorwosidKarkucak, Murat/IZP-8842-2023
dc.contributor.authorBodur, Hatice
dc.contributor.authorAtaman, Sebnem
dc.contributor.authorRezvani, Aylin
dc.contributor.authorBugdayci, Derya Soy
dc.contributor.authorCevik, Remzi
dc.contributor.authorBirtane, Murat
dc.contributor.authorAkinci, Aysen
dc.date.accessioned2024-08-04T21:00:57Z
dc.date.available2024-08-04T21:00:57Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]). The mean ASQoL score was 7.1 +/- A 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL. In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales.en_US
dc.description.sponsorshipWyeth/Pfizer Companyen_US
dc.description.sponsorshipThe authors express their gratitude to all members of the TRASD AS Study group for their cooperation and to Wyeth/Pfizer Company for the registery sponsorship.en_US
dc.identifier.doi10.1007/s11136-010-9771-9
dc.identifier.endpage549en_US
dc.identifier.issn0962-9343
dc.identifier.issn1573-2649
dc.identifier.issue4en_US
dc.identifier.pmid20978859en_US
dc.identifier.startpage543en_US
dc.identifier.urihttps://doi.org/10.1007/s11136-010-9771-9
dc.identifier.urihttps://hdl.handle.net/11616/103964
dc.identifier.volume20en_US
dc.identifier.wosWOS:000289481100010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofQuality of Life Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing spondylitisen_US
dc.subjectQuality of lifeen_US
dc.titleQuality of life and related variables in patients with ankylosing spondylitisen_US
dc.typeArticleen_US

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