Is lymph node ratio prognostic factor for survival in elderly patients with node positive breast cancer? The Anatolian Society of Medical Oncology

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dc.authoridGöksel, Gamze/0000-0002-7991-0036
dc.authoridDEMIRCI, UMUT/0000-0002-4833-6721
dc.authorwosidunal, olcun umit/IST-6684-2023
dc.authorwosidDogu, Gamze Gokoz/A-9815-2010
dc.authorwosidGöksel, Gamze/HHC-6548-2022
dc.authorwosidcolak, dilsen/GRY-5456-2022
dc.authorwosidGeredeli, Caglayan/AAN-4122-2020
dc.contributor.authorInal, Ali
dc.contributor.authorAkman, Tulay
dc.contributor.authorYaman, Sebnem
dc.contributor.authorOzturk, Selcuk Cemil
dc.contributor.authorGeredeli, Caglayan
dc.contributor.authorBilici, Mehmet
dc.contributor.authorInanc, Mevlude
dc.date.accessioned2024-08-04T20:59:47Z
dc.date.available2024-08-04T20:59:47Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSeveral studies have now demonstrated that the lymph node ratio (LNR), as a superior indicator of axillary tumor burden to the number of excised nodes. While, about the prognostic value of LNR on the the survival of elderly patients is limited. The aim of this retrospective multicenter study is to evaluate the prognostic value of lymph node ratio in elderly patients with node positive breast cancer. METHODS: Onehundredeightyfour patient with operable breast cancer, recruited from 17 institutions, were enrolled into the retrospectively study. Eleven potential prognostic variables were chosen for analysis in this study. Univariate and multivariate analyses were conducted to identify prognostic factors associated with survival. RESULT: Among the eleven variables of univariate analysis, four variables were identified to have prognostic significance for Overall survival (OS): pathologic tumor size (T), No. of positive nodes (N), LNR and estrogen receptor-positive (ER). Among the eleven variables of univariate analysis, two variables were identified to have prognostic significance for Disease-free survival (DFS): N and LNR. Multivariate analysis by Cox proportional hazard model showed that 7; LNR and ER were considered independent prognostic factors for OS. Furthermore, LNR was considered independent prognostic factors for DFS. CONCLUSION: In conclusion, the LNR was associated with the prognostic importance for DFS and OS in elderly patients who were administered adjuvant treatments.en_US
dc.identifier.endpage148en_US
dc.identifier.issn0003-469X
dc.identifier.issn2239-253X
dc.identifier.issue2en_US
dc.identifier.pmid23698146en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://hdl.handle.net/11616/103519
dc.identifier.volume84en_US
dc.identifier.wosWOS:000320292300004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Luigi Pozzien_US
dc.relation.ispartofAnnali Italiani Di Chirurgiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast canceren_US
dc.subjectElderly patientsen_US
dc.subjectLymph Node Ratioen_US
dc.titleIs lymph node ratio prognostic factor for survival in elderly patients with node positive breast cancer? The Anatolian Society of Medical Oncologyen_US
dc.typeArticleen_US

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