Adenosine deaminase level in the serum of the patients Toxoplasma gondii seropositive and Giardia intestinalis

dc.authoridKIRAN, TUGBA RAIKA/0000-0002-3724-0249
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridKıran, Tugba Raika/0000-0002-3724-0249
dc.authorwosidKIRAN, TUGBA RAIKA/AAA-8224-2021
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidKıran, Tugba Raika/HFZ-9643-2022
dc.contributor.authorKaraman, Uelkue
dc.contributor.authorBeytur, Leyla
dc.contributor.authorKiran, Tugba Raika
dc.contributor.authorColak, Cemil
dc.date.accessioned2024-08-04T20:56:23Z
dc.date.available2024-08-04T20:56:23Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAdenosine deaminase (ADA) is an aminohydrolase making adenosine, deoksiadenozini inozin, and deocsiniozine deaminise irreversibly and plays role in the catabolism of purine nucleotids. Toxoplasma gondii is a zoonoses intracellular parasite that causes infection in animals and humans. This parasite encompasses enzymes that produce free radicals such as superoxide and hydrogen peroxide. In addition, Giardia intestinalis is another parasite that causes irritations in mucosa, over mucus discharge, aggravating former inflammations, and various absorption defects. In the present study, it has been aimed to compare ADA levels between T. gondii seropositive (IgG seropositive but symptomless patients), G. intestinalis positive patients, and control group. Thus, ADA levels between 32 patients being T. gondii seropositive and 29 controls and between 50 patients' G. intestinalis positive and 40 controls have been evaluated. The results were analyzed using independent samples t-test at the level of p < 0.05. According to this, in the statistical comparison between the parameters of patient and control groups, a meaningful decrease could be determined in ADA levels. This situation can be commented in the way that toxoplasmosis infection being inactive does not necessarily cause an increase in T lymphocytes. In addition, this decrease can be due to increasing oxidative stress in parasitic infections.en_US
dc.identifier.endpage657en_US
dc.identifier.issn1996-0808
dc.identifier.issue10en_US
dc.identifier.startpage654en_US
dc.identifier.urihttps://hdl.handle.net/11616/102278
dc.identifier.volume3en_US
dc.identifier.wosWOS:000275387100014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.ispartofAfrican Journal of Microbiology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectToxoplasma gondiien_US
dc.subjectGiardia intestinalisen_US
dc.subjectadenosine deaminaseen_US
dc.titleAdenosine deaminase level in the serum of the patients Toxoplasma gondii seropositive and Giardia intestinalisen_US
dc.typeArticleen_US

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