Electroanalytical determination of reduced-glutathione in biological samples

dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorSavan, Ebru Kuyumcu
dc.date.accessioned2024-08-04T20:58:38Z
dc.date.available2024-08-04T20:58:38Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: In this study, it was aimed to determine the reduced Glutathione (GSH) at the modified sensor with a simple and reliable electroanalytical method. Material and Method: Cyclic voltammetry and differential pulse voltammetry techniques were used for the determination of reduced-GSH. And the modified sensor was fabricated by dropping single-walled carbon nanotube (SWCNT) dispersion onto the surface of the glassy carbon electrode. Results: The determination of reduced-GSH was accomplished at SWCNT modified sensor. The relationship between the current responses of the sensor and the concentrations of the reduced-GSH (1.0 x 10-(8) - 5.0 x 10-(8) M) showed excellent linearity and the detection limit was calculated as 75 nM. Discussion: Determination of trace amounts of reduced-GSH in urine samples was successfully applied at the modified sensor. The results showed that modification of the glassy carbon electrode with SWCNT could provide a new strategy for determining the concentration of GSH in physiological solutions.en_US
dc.identifier.doi10.4328/JCAM.6155
dc.identifier.endpage397en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.issue3en_US
dc.identifier.startpage394en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.6155
dc.identifier.urihttps://hdl.handle.net/11616/103036
dc.identifier.volume10en_US
dc.identifier.wosWOS:000475294300019en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGSHen_US
dc.subjectElectrochemical Sensoren_US
dc.subjectVoltammetryen_US
dc.titleElectroanalytical determination of reduced-glutathione in biological samplesen_US
dc.typeArticleen_US

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