Electroanalytical determination of reduced-glutathione in biological samples
dc.authorid | Kuyumcu Savan, Ebru/0000-0002-8851-0907 | |
dc.authorwosid | Kuyumcu Savan, Ebru/E-3430-2019 | |
dc.contributor.author | Savan, Ebru Kuyumcu | |
dc.date.accessioned | 2024-08-04T20:58:38Z | |
dc.date.available | 2024-08-04T20:58:38Z | |
dc.date.issued | 2019 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Aim: In this study, it was aimed to determine the reduced Glutathione (GSH) at the modified sensor with a simple and reliable electroanalytical method. Material and Method: Cyclic voltammetry and differential pulse voltammetry techniques were used for the determination of reduced-GSH. And the modified sensor was fabricated by dropping single-walled carbon nanotube (SWCNT) dispersion onto the surface of the glassy carbon electrode. Results: The determination of reduced-GSH was accomplished at SWCNT modified sensor. The relationship between the current responses of the sensor and the concentrations of the reduced-GSH (1.0 x 10-(8) - 5.0 x 10-(8) M) showed excellent linearity and the detection limit was calculated as 75 nM. Discussion: Determination of trace amounts of reduced-GSH in urine samples was successfully applied at the modified sensor. The results showed that modification of the glassy carbon electrode with SWCNT could provide a new strategy for determining the concentration of GSH in physiological solutions. | en_US |
dc.identifier.doi | 10.4328/JCAM.6155 | |
dc.identifier.endpage | 397 | en_US |
dc.identifier.issn | 1309-0720 | |
dc.identifier.issn | 1309-2014 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 394 | en_US |
dc.identifier.uri | https://doi.org/10.4328/JCAM.6155 | |
dc.identifier.uri | https://hdl.handle.net/11616/103036 | |
dc.identifier.volume | 10 | en_US |
dc.identifier.wos | WOS:000475294300019 | en_US |
dc.identifier.wosquality | N/A | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.language.iso | en | en_US |
dc.publisher | Derman Medical Publ | en_US |
dc.relation.ispartof | Journal of Clinical and Analytical Medicine | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | GSH | en_US |
dc.subject | Electrochemical Sensor | en_US |
dc.subject | Voltammetry | en_US |
dc.title | Electroanalytical determination of reduced-glutathione in biological samples | en_US |
dc.type | Article | en_US |