Clinical and ımaging findings in childhood posterior reversible encephalopathy syndrome
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Iranıan journal of chıld neurology
Erişim Hakkı
info:eu-repo/semantics/restrictedAccess
Özet
Objective
Posterior reversible encephalopathy syndrome (PRES) is characterized by typical radiologic findings in the posterior regions of the cerebral hemispheres and cerebellum. The symptoms include headache, nausea, vomiting, visual disturbances, focal neurologic deficits, and seizures. The aim of this study is to evaluate the clinical and radiological features of PRES in children and to emphasize the recognition of atypical features.
Materials & Methods
We retrospectively examined 23 children with PRES from Mar 2010-Apr 2015 in Inonu University Turgut Ozal Medical Center in Turkey. We compared the clinical features and cranial MRI findings between underlying diseases of PRES.
Results
The most common precipitating factors were hypertension (78.2%) and medications, namely immunosuppressive and antineoplastic agents (60.8%). Manifestations included mental changes (100%), seizures (95.6%), headache (60.8%), and visual disturbances (21.7%) of mean 3.6 (range 1-10) days' duration. Cranial magnetic resonance imaging (MRI) showed bilateral occipital lesions in all patients, associated in 82.6% with less typical distribution of lesions in frontal, temporal or parietal lobes, cerebellum, corpus callosum, basal ganglia, thalamus, and brain stem. Frontal involvement was predominant, observed in 56.5% of patients. Clinical recovery was followed by radiologic resolution in all patients.
Conclusion
PRES is often unsuspected by the clinician, thus radiologists may be the first to suggest this diagnosis on an MRI obtained for seizures or encephalopathy. Atypical MRI finding is seen quite often. Rapid diagnosis and treatment are required to avoid a devastating outcome.
Açıklama
Anahtar Kelimeler
Children, Posterior reversible encephalopathy syndrome, Seizure, Atypical radiological finding
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
12
Sayı
1
Künye
Gungor, S. Kilic, B. Tabel, Y. Selimoglu, A. Ozgen, U. Yilmaz, S. Sigirci, A. (2018). Clinical and ımaging findings in childhood posterior reversible encephalopathy syndrome.Cilt:12. Sayı:1. 16-25.ss.
