The importance of serum and ascites fluid alpha-fetoprotein, carcinoembryonic antigen, CA 19-9, and CA 15-3 levels in differential diagnosis of ascites etiology

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dc.authoridHilmioğlu, Fatih/0000-0002-6440-5686
dc.authoridSevinç, Alper/0000-0002-0499-8918
dc.authorwosidSari, Ramazan/C-2868-2016
dc.authorwosidHilmioğlu, Fatih/AAJ-4437-2021
dc.authorwosidSevinc, Alper/KFQ-6440-2024
dc.authorwosidSari, Funda/C-7068-2016
dc.authorwosidSevinç, Alper/KPA-4519-2024
dc.contributor.authorSari, R
dc.contributor.authorYildirim, B
dc.contributor.authorSevinc, A
dc.contributor.authorBahceci, F
dc.contributor.authorHilmioglu, F
dc.date.accessioned2024-08-04T21:02:05Z
dc.date.available2024-08-04T21:02:05Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Aims: Clinical usage of tumor markers is being limited due to low specificity. Elevated plasma levels of tumor markers may be seen in diseases other than malignancy, i.e., kidney, liver or circulatory disturbances. Methodology: In our study, we studied serum and ascites fluid alpha-fetoprotein, carcinoembryonic antigen, CA 19-9, CA 15-3 levels in patients with chronic liver disease, spontaneous bacterial peritonitis, malignancy, tuberculous and congestive heart failure in a total of 76 patients. Results: The sensitivity and specificity for ascites fluid alpha-fetoprotein levels were 28.5% and 100%, for serum alpha-fetoprotein levels 28.5% and 98.1%, for ascites fluid carcinoembryonic antigen levels 38.0% and 98.1%, for serum carcinoembryonic antigen levels 57.1% and 90.0%, for ascites fluid CA 19-9 levels 19.0% and 94.5%, for serum CA 19-9 levels 33.3% and 21.8%, for ascites fluid CA 15-3 levels 28.5% and 92.7%, and for serum CA 15-3 levels 47.6% and 81.8%, respectively. Conclusions: In conclusion, the sensitivity of serum and ascites fluid tumor markers was found to be low. High specificity may be due to low number of study participants. Serum and ascites fluid tumor markers are not found to be useful in the differential diagnosis of ascites etiology.en_US
dc.identifier.endpage1621en_US
dc.identifier.issn0172-6390
dc.identifier.issue42en_US
dc.identifier.pmid11813585en_US
dc.identifier.startpage1616en_US
dc.identifier.urihttps://hdl.handle.net/11616/104467
dc.identifier.volume48en_US
dc.identifier.wosWOS:000172705600022en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherH G E Update Medical Publishing S Aen_US
dc.relation.ispartofHepato-Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttumor markersen_US
dc.subjectascitesen_US
dc.subjectdiagnosisen_US
dc.titleThe importance of serum and ascites fluid alpha-fetoprotein, carcinoembryonic antigen, CA 19-9, and CA 15-3 levels in differential diagnosis of ascites etiologyen_US
dc.typeArticleen_US

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