Predictors of mortality in septic shock: findings for 57 patients diagnosed on admission to emergency or within 24 hours of admission to intensive care

Basit Öğe Kaydı
dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridGedik, Ender/0000-0002-7175-207X
dc.authoridYucel, Neslihan/0000-0001-5845-2614
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.authorwosidGedik, Ender/ABI-2971-2020
dc.authorwosidYucel, Neslihan/ABI-3412-2020
dc.contributor.authorYucel, N.
dc.contributor.authorTogal, T.
dc.contributor.authorGedik, E.
dc.contributor.authorErtan, C.
dc.contributor.authorKayabas, U.
dc.contributor.authorAkgun, F. S.
dc.contributor.authorBayindir, Y.
dc.date.accessioned2024-08-04T21:00:12Z
dc.date.available2024-08-04T21:00:12Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To identify the risk factors that influence outcome for patients who are diagnosed with septic shock in the emergency department at presentation or within 24 hours after admission to intensive care unit. Methods: A retrospective study of 57 adult patients with septic shock was conducted between March 1, 2006 and August 31, 2009. Results: The patients were 23 males and 34 females with a median age of 67 years (20 to 92 years). Thirty-three (58%) of 57 patients died in hospital and 24 (42%) survived. Multivariate analysis identified low blood pH (OR <0.001; 95% CI <0.001-0.53) and low bicarbonate level (OR 0.81; 95% CI 0.70-0.95) at emergency department or intensive care unit admission as useful predictors of 3-day in-hospital mortality. Low blood pH (OR <0.001; 95% CI <0.001-0.05), low bicarbonate level (OR 0.75; 95% CIs 0.61-0.91), long duration of symptoms (OR 1.49; 95% CI 1.04-2.13), high MEDS score (OR 1.56; 95% CIs 1.06-2.30), and high SOFA score (OR 1.57; 95% CI 1.12-2.20) were risk factors for 14-day in-hospital mortality. Renal failure (OR 7.58; 95% CI 1.28-44.77), lower pulmonary tract infection (OR 3.58; 95% CI 1.10-11.58), high MEDS score (OR 1.42; 95% CI 1.05-1.93) and high APACHE II score (OR 1.34; 95% CI 1.13-1.60) were risk factors for 28-day in-hospital mortality. Conclusions: Several factors signaling poor short-term outcome for this patient group are low blood pH, low serum bicarbonate level, longer duration of symptoms lower respiratory tract infection and renal failure. MEDS and SOFA scores might be helpful in the ED to stratify patients with septic shock according to mortality risk. (Hong Kong j. emerg.med. 2012;19:375-386)en_US
dc.identifier.endpage386en_US
dc.identifier.issn1024-9079
dc.identifier.issn2309-5407
dc.identifier.issue6en_US
dc.identifier.startpage375en_US
dc.identifier.urihttps://hdl.handle.net/11616/103889
dc.identifier.volume19en_US
dc.identifier.wosWOS:000311600100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHong Kong Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEmergency medical serviceen_US
dc.subjectfatal outcomeen_US
dc.subjectmortalityen_US
dc.subjectrisk factorsen_US
dc.subjectsepsisen_US
dc.titlePredictors of mortality in septic shock: findings for 57 patients diagnosed on admission to emergency or within 24 hours of admission to intensive careen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu