Association of Helicobacter pylori infection with systemic inflammation in preeclampsia

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dc.authorid101949en_US
dc.contributor.authorÜstün, Yusuf
dc.contributor.authorÜstün, Yaprak Engin
dc.contributor.authorÖzkaplan, Esra
dc.contributor.authorOtlu, Barış
dc.contributor.authorTekerekoğlu, Mehmet Sait
dc.date.accessioned2017-07-15T07:37:25Z
dc.date.available2017-07-15T07:37:25Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective. The aim of this study was to compare C-reactive protein (CRP), tumor necrosis factor alpha (TNFa), Chlamydia pneumonia IgG, IgM and plasma Helicobacter pylori IgA levels between preeclamptic and normal pregnant women and to determine whether seropositivity to Helicobacter pylori is associated with elevated levels of CRP and TNF-a. Methods. Forty patients with preeclampsia and 40 normotensive pregnant women of similar age and body mass index at the third trimester of gestation were selected for the study. Chlamydia pneumonia IgM and IgGs, Helicobacter pylori IgAs and concentrations of CRP and TNF-a were measured. Results. Concentrations of CRP and TNF-a were significantly higher in patients with preeclampsia than in control subjects. In the preeclamptic group, positivity rate for Helicobacter pylori IgA was significantly higher as compared to controls (p ¼ 0.034). CRP and TNF-a levels were higher in Helicobacter pylori seropositive subjects. Conclusion. We demonstrated high levels of serum CRP and TNF-a in preeclamptic women who were seropositive to Helicobacter pylori in comparison with those in seronegative subjects.en_US
dc.identifier.citationÜstün, Y. Üstün, Y. E. Özkaplan, E. Otlu, B. Tekerekoğlu, M. S. (2010). Association of Helicobacter pylori infection with systemic inflammation in preeclampsia. Journal of Maternal-Fetal & Neonatal Medicine. 23(4), 311–314.en_US
dc.identifier.endpage314en_US
dc.identifier.issue4en_US
dc.identifier.startpage311en_US
dc.identifier.urihttps://hdl.handle.net/11616/7385
dc.identifier.volume23en_US
dc.language.isoenen_US
dc.publisherJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPreeclampsiaen_US
dc.subjectHelicobacter pylorien_US
dc.subjectChlamydia pneumoniaen_US
dc.subjectC-reactive proteinen_US
dc.subjectTumor necrosis factor alphaen_US
dc.titleAssociation of Helicobacter pylori infection with systemic inflammation in preeclampsiaen_US
dc.typeArticleen_US

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