The Risk Factors Affecting Length of Stay and Mortality in Covid 19 Patients: Laboratory Parameters, Comorbidities, and Demographic Characteristics
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Duzce Univ, Fac Medicine
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Covid 19 can cause fatal pneumonia and serious complications. In the course of the disease the levels of different biochemical parameters increased and these parameters provide important information about the prognosis of the disease. The aim of this study was to investigate the relationship between biochemical parameters and length of stay and mortality in Covid 19 patients. Methods: In this retrospective study, a total of 767 Covid 19 patients hospitalized in our hospital were included. The demographic characteristics, length of stay, comorbid diseases and biochemical parameters of the patients were scanned from the hospital's database and patient files and recorded. Patients were grouped according to the length of stay; 1st Group: 7 days and less, 2nd Group: 8-10 days, 3rd Group: 11-13 days, and 4th Group: 14 days and more. Results: The mean CRP level was significantly higher in group 4 compared to group 1 (p = 0.002). The mean levels of LDH, PRO_BNP, and procalcitonin were significantly higher in group 4 compared to group 1 and group 2 (p <0.001, p = 0.026, p = 0.007, respectively). The mean level of fibrinogen was significantly higher in group 4 compared to group 2 (p = 0.011). Presence of DM and HT as comorbidities (p = 0.022, p = 0.006) and high levels of LDH and ferritin (p <0.001, p = 0.041) significantly increased the risk of death. Conclusions: The results of our study show that positive correlation between the levels of CRP, LDH, PCT, PROBNP, and fibrinogen the prolongation of hospitalization in Covid 19 patients and these parameters can be associated with the severity disease. These results show that increased levels of LDH and ferritin, age, prolongation of hospitalization, and the presence of HT and DM increase mortality rate and can be specific parameters in terms of prognosis.
Açıklama
Anahtar Kelimeler
Covid 19, Laboratory Tests, Mortality, Comorbidity Diseases, CRP, LDH
Kaynak
Konuralp Tip Dergisi
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
13
