Ceftriaxone associated biliary pseudolithiasis in paediatric surgical patients

Yükleniyor...
Küçük Resim

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

International Journal of Antimicrobial Agents

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

It is well known that ceftriaxone leads to pseudolithiasis in some patients. Clinical and experimental studies also suggest that situations causing gallbladder dysfunction, such as fasting, may have a role for the development of pseudolithiasis. In this study, we prospectively evaluated the incidence and clinical importance of pseudolithiasis in paediatric surgical patients receiving ceftriaxone treatment, who often had to fast in the post-operative period. Fifty children who were given ceftriaxone were evaluated by serial abdominal sonograms. Of those, 13 (26%) developed biliary pathology. Comparison of the patients with or without pseudolithiasis revealed no significant difference with respect to age, sex, duration of the treatment and starvation variables. After cessation of the treatment, pseudolithiasis resolved spontaneously within a short period. The incidence of pseudolithiasis is not affected by fasting.

Açıklama

Anahtar Kelimeler

Pseudolithiasis, Ceftriaxone, Cholelithiasis, Gallbladder

Kaynak

International Journal of Antimicrobial Agents

WoS Q Değeri

Scopus Q Değeri

Cilt

25

Sayı

Künye

Ceran Özcan, C. Öztoprak, İ. Cankorkmaz, L. Gümüş, C. Yıldız, T. Köylüoğlu, G. (2005). Ceftriaxone associated biliary pseudolithiasis in paediatric surgical patients. International Journal of Antimicrobial Agents. 25 ; 256–259.