Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysis
dc.authorid | ersoy, F. Fevzi/0000-0001-9722-1560 | |
dc.authorid | taskapan, hulya/0000-0001-8736-4779 | |
dc.authorid | camsari, taner/0000-0001-8293-3688 | |
dc.authorwosid | ersoy, F. Fevzi/C-1815-2016 | |
dc.authorwosid | Akpolat, Tekin/IAM-7772-2023 | |
dc.authorwosid | Gültekin, Meral/C-1835-2016 | |
dc.authorwosid | taskapan, hulya/ABI-7737-2020 | |
dc.authorwosid | Ataman, Muveddet Rezzan/AAA-9042-2020 | |
dc.authorwosid | camsari, taner/C-9048-2015 | |
dc.contributor.author | Taskapan, H. | |
dc.contributor.author | Ersoy, F. F. | |
dc.contributor.author | Passadakis, P. S. | |
dc.contributor.author | Tam, P. | |
dc.contributor.author | Memmos, D. E. | |
dc.contributor.author | Katopodis, K. P. | |
dc.contributor.author | Ozener, C. | |
dc.date.accessioned | 2024-08-04T21:01:09Z | |
dc.date.available | 2024-08-04T21:01:09Z | |
dc.date.issued | 2006 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | The aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers. Method: This cross-sectional, multicenter study was carried out in 273 PD patients with a mean age of 61.7 +/- 10.9 years and mean duration of PD 3.3 +/- 2.2 years. It included 123 female and 150 male patients from 20 centers in Greece and Turkey, countries that are on the same latitude, namely, 36 - 42 degrees north. We measured 25(OH)D-3 and 1.25(OH)(2)D-3 levels and some other clinical and laboratory indices of bone mineral metabolism. Results: Of these 273 patients 92% (251 patients) had vitamin D deficiency i.e. serum 25(OH)D-3 levels less than 15 ng/ml, 119 (43.6%) had severe vitamin D deficiency i.e. serum 25(OH)D-3 levels, less than 5 ng/ml, 132 (48.4%) had moderate vitamin D deficiency i.e. serum 25(OH)D3 levels, 5 - 15 ng/ml, 12 (4.4%) vitamin D insufficiency i.e. serum 25(OH)D3 levels 15 - 30 ng/ml and only 10 (3.6%) had adequate vitamin D stores. We found no correlation between 25(OH)D-3 levels and PTH, serum albumin, bone alkaline phosphatase, P, and Ca x P. In multiple regression analyses, the independent predictors of 25(OH)D-3 were age, presence of diabetes (DM-CRF), levels of serum calcium and serum 1.25(OH)(2)D-3- Conclusion: We found a high prevalence (92%) of vitamin D deficiency in these 273 PD patients, nearly one half of whom had severe vitamin D deficiency. Vitamin D deficiency is more common in DM-CRF patients than in non-DM-CRF patients. Our findings suggest that these patients should be considered for vitamin D supplementation. | en_US |
dc.identifier.endpage | 255 | en_US |
dc.identifier.issn | 0301-0430 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.pmid | 17063991 | en_US |
dc.identifier.startpage | 247 | en_US |
dc.identifier.uri | https://hdl.handle.net/11616/104123 | |
dc.identifier.volume | 66 | en_US |
dc.identifier.wos | WOS:000241194700004 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Dustri-Verlag Dr Karl Feistle | en_US |
dc.relation.ispartof | Clinical Nephrology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | vitamin D deficiency | en_US |
dc.subject | serum 25(OH)D | en_US |
dc.subject | dialysis | en_US |
dc.subject | chronic renal failure | en_US |
dc.title | Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysis | en_US |
dc.type | Article | en_US |