Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysis

dc.authoridersoy, F. Fevzi/0000-0001-9722-1560
dc.authoridtaskapan, hulya/0000-0001-8736-4779
dc.authoridcamsari, taner/0000-0001-8293-3688
dc.authorwosidersoy, F. Fevzi/C-1815-2016
dc.authorwosidAkpolat, Tekin/IAM-7772-2023
dc.authorwosidGültekin, Meral/C-1835-2016
dc.authorwosidtaskapan, hulya/ABI-7737-2020
dc.authorwosidAtaman, Muveddet Rezzan/AAA-9042-2020
dc.authorwosidcamsari, taner/C-9048-2015
dc.contributor.authorTaskapan, H.
dc.contributor.authorErsoy, F. F.
dc.contributor.authorPassadakis, P. S.
dc.contributor.authorTam, P.
dc.contributor.authorMemmos, D. E.
dc.contributor.authorKatopodis, K. P.
dc.contributor.authorOzener, C.
dc.date.accessioned2024-08-04T21:01:09Z
dc.date.available2024-08-04T21:01:09Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers. Method: This cross-sectional, multicenter study was carried out in 273 PD patients with a mean age of 61.7 +/- 10.9 years and mean duration of PD 3.3 +/- 2.2 years. It included 123 female and 150 male patients from 20 centers in Greece and Turkey, countries that are on the same latitude, namely, 36 - 42 degrees north. We measured 25(OH)D-3 and 1.25(OH)(2)D-3 levels and some other clinical and laboratory indices of bone mineral metabolism. Results: Of these 273 patients 92% (251 patients) had vitamin D deficiency i.e. serum 25(OH)D-3 levels less than 15 ng/ml, 119 (43.6%) had severe vitamin D deficiency i.e. serum 25(OH)D-3 levels, less than 5 ng/ml, 132 (48.4%) had moderate vitamin D deficiency i.e. serum 25(OH)D3 levels, 5 - 15 ng/ml, 12 (4.4%) vitamin D insufficiency i.e. serum 25(OH)D3 levels 15 - 30 ng/ml and only 10 (3.6%) had adequate vitamin D stores. We found no correlation between 25(OH)D-3 levels and PTH, serum albumin, bone alkaline phosphatase, P, and Ca x P. In multiple regression analyses, the independent predictors of 25(OH)D-3 were age, presence of diabetes (DM-CRF), levels of serum calcium and serum 1.25(OH)(2)D-3- Conclusion: We found a high prevalence (92%) of vitamin D deficiency in these 273 PD patients, nearly one half of whom had severe vitamin D deficiency. Vitamin D deficiency is more common in DM-CRF patients than in non-DM-CRF patients. Our findings suggest that these patients should be considered for vitamin D supplementation.en_US
dc.identifier.endpage255en_US
dc.identifier.issn0301-0430
dc.identifier.issue4en_US
dc.identifier.pmid17063991en_US
dc.identifier.startpage247en_US
dc.identifier.urihttps://hdl.handle.net/11616/104123
dc.identifier.volume66en_US
dc.identifier.wosWOS:000241194700004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDustri-Verlag Dr Karl Feistleen_US
dc.relation.ispartofClinical Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectvitamin D deficiencyen_US
dc.subjectserum 25(OH)Den_US
dc.subjectdialysisen_US
dc.subjectchronic renal failureen_US
dc.titleSevere vitamin D deficiency in chronic renal failure patients on peritoneal dialysisen_US
dc.typeArticleen_US

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