Trabeculectomy with brief exposure of mitomycin C

dc.authoridBayramlar, Huseyin/0000-0002-8118-1151
dc.authorwosidBayramlar, Huseyin/I-5876-2013
dc.contributor.authorHepsen, IF
dc.contributor.authorBayramlar, H
dc.contributor.authorOram, O
dc.date.accessioned2024-08-04T21:02:17Z
dc.date.available2024-08-04T21:02:17Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, mitomycin-C (MMC) al a concentration of 0.2 mg/mL was applied intraoperatively for 1 minute in 11 consecutive primary trabeculectomies to increase the success of glaucoma-filtration surgery while minimizing the incidence of postoperative complications resulting from MMC use. The success criteria included a postoperative intraocular pressure (IOP) lower than 21 mmHg without treatment, a 20% or more drop from preoperative IOP levels, and a visual loss limited to one or fewer lines of Snellen acuity. The procedure was considered successful in 10 eyes (90.9%), with a mean follow-up period of 25.6 weeks. Blebs were ischemic and microcystic in all successful eyes at the time of the last follow up. Postoperative complications included subconjunctival hemorrhage, hyphema, conjunctival wound leak, and corneal epithelial defects. Complications related to low IOP, such as choroidal detachment and hypotonic maculopathy, were not seen in any of the eyes. Although the longer term of follow-up results of this regimen are not well known, this alternative intraoperative application of MMC at a concentration of 0.2 mg/mL for 1 minute seems to control postoperative IOP effectively in primary trabeculectomies with fewer hypotony-related complications.en_US
dc.identifier.endpage83en_US
dc.identifier.issn1079-4794
dc.identifier.issue2en_US
dc.identifier.startpage80en_US
dc.identifier.urihttps://hdl.handle.net/11616/104623
dc.identifier.volume28en_US
dc.identifier.wosWOS:A1996UK73600005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAmer Soc Contemporary Ophthalmologyen_US
dc.relation.ispartofAnnals of Ophthalmology-Glaucomaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRefractory Glaucomaen_US
dc.subjectHypotonyen_US
dc.titleTrabeculectomy with brief exposure of mitomycin Cen_US
dc.typeArticleen_US

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