The frequency of HLA A, B, C, DP, DQ, DR allele in patients of Turkish and Syrian nationals with allogeneic stem cell transplantation

dc.authoridErkurt, Mehmet Ali/0000-0002-3285-417X
dc.authoridSARICI, Ahmet/0000-0002-5916-0119
dc.authoridKAYA, Emin/0000-0001-8605-8497
dc.authoridYagin, Fatma Hilal/0000-0002-9848-7958
dc.authoridBİÇİM, SOYKAN/0000-0001-7498-344X
dc.authorwosidErkurt, Mehmet Ali/ABI-7232-2020
dc.authorwosidSARICI, Ahmet/ABI-7512-2020
dc.authorwosidKAYA, Emin/W-2951-2017
dc.authorwosidYagin, Fatma Hilal/ABI-8066-2020
dc.authorwosidBİÇİM, SOYKAN/ACZ-6163-2022
dc.contributor.authorKaya, Ahmet
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorKuku, Irfan
dc.contributor.authorKaya, Emin
dc.contributor.authorBerber, Ilhami
dc.contributor.authorBicim, Soykan
dc.contributor.authorHidayet, Emine
dc.date.accessioned2024-08-04T21:02:03Z
dc.date.available2024-08-04T21:02:03Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: In allogeneic stem cell transplantation, donor and recipient HLA tissue compatibility is essential for the success of stem cell transplantation. HLA tissue compatibility percentage is the most important parameter that increases the success of transplantation in donor selection. Pretransplant HLA tissue typing can be looked at in low and high resolution according to the facilities of the center and the urgency of transplantation. Many centers evaluate HLA HLA-A, B, C, DP, DQ, DR tissue types before allogeneic bone marrow transplantation. HLA tissue types differ in many races and even between unrelated individuals of the same race. AIMS: This study aimed to show the common human leukocyte antigen (HLA) rates and differences in Syrian and Turkish ethnicity patients who underwent allogeneic stem cell transplantation in our center. MATERIALS AND METHODS: HLA tissue similarities between Turkish and Syrian patients were revealed by examining the HLA tissue records of Turkish and Syrian patients who applied to the bone marrow transplant unit of Inonu University Turgut Ozal Medical Center between December 2009 and November 2021 for allogeneic stem cell transplantation. RESULTS: As a result of our study, it has been observed that there are similarities in terms of HLA A*02, HLA B*35, HLA C 04,07,12, HLA DP*02,04,11 HLA DQ*02,03,05,06, HLA DR*01,03,11,13 in Turkish and Syrian patients. High resolution HLA subgroups of the patients are shown in Tables three and four. CONCLUSION: In allogeneic stem cell transplantation, there may be similar HLA tissue types among ethnic groups.en_US
dc.identifier.doi10.4103/ijh.ijh_21_22
dc.identifier.endpage117en_US
dc.identifier.issn2072-8069
dc.identifier.issn2543-2702
dc.identifier.issue2en_US
dc.identifier.startpage110en_US
dc.identifier.urihttps://doi.org/10.4103/ijh.ijh_21_22
dc.identifier.urihttps://hdl.handle.net/11616/104446
dc.identifier.volume11en_US
dc.identifier.wosWOS:000900393800004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofIraqi Journal of Hematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllogeneic stem cell transplantationen_US
dc.subjectethnicityen_US
dc.subjecthuman leukocyte antigen tissue typesen_US
dc.titleThe frequency of HLA A, B, C, DP, DQ, DR allele in patients of Turkish and Syrian nationals with allogeneic stem cell transplantationen_US
dc.typeArticleen_US

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