The Relation Between C-Reactive Protein-Albumin Ratio and Carotid Intima-Media Thickness in Psoriasis

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dc.authoridBalta, Ilknur/0000-0002-0909-589X
dc.authoridBalta, Sevket/0000-0002-6657-7334
dc.contributor.authorBalta, Ilknur
dc.contributor.authorBalta, Sevket
dc.date.accessioned2024-08-04T21:02:10Z
dc.date.available2024-08-04T21:02:10Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPsoriasis vulgaris is associated with an increased risk of atherosclerosis. The C-Reactive Protein-to-Albumin Ratio (CAR) has received increasing attention as an independent prognostic factor for inflammatory diseases. The carotid intima-media thickness (cIMT) is a predictor of atherosclerosis. We assessed the correlation between CAR and cIMT in patients with psoriasis vulgaris. We enrolled 147 participants (72 with psoriasis vulgaris and 75 controls). Disease severity was assessed using the Psoriasis Area Severity Index (PASI). Patient and control groups were similar with regard to gender, age, and body mass index (BMI). cIMT was measured in both the left and the right common carotid arteries. CAR values were higher in patients with psoriasis compared with controls (0.93 (0.06-4.32) vs 0.51 (0.10-2.99), p < .001). The patients with psoriasis had a significantly greater cIMT compared with control subjects. (0.53 (0.42-0.65) vs 0.50 (0.41-0.65) mm, p = .03). PASI scores were positively correlated with CAR values (r = 0.532, p < .001). A positive correlation between cIMT and CAR was found in patients with psoriasis vulgaris (r = 0.463, p < .001). CAR is an easily derived reproducible marker that could prove useful for assessing the inflammatory status of patients with psoriasis in clinical practice. CAR may also prove useful as a cardiovascular risk marker in these patients.en_US
dc.identifier.doi10.1177/00033197211072599
dc.identifier.endpage780en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue8en_US
dc.identifier.pmid35189713en_US
dc.identifier.startpage772en_US
dc.identifier.urihttps://doi.org/10.1177/00033197211072599
dc.identifier.urihttps://hdl.handle.net/11616/104528
dc.identifier.volume73en_US
dc.identifier.wosWOS:000772339000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpsoriasis vulgarisen_US
dc.subjectatherosclerosisen_US
dc.subjectC-reactive protein-albumin ratioen_US
dc.subjectcarotid intima-media thicknessen_US
dc.titleThe Relation Between C-Reactive Protein-Albumin Ratio and Carotid Intima-Media Thickness in Psoriasisen_US
dc.typeArticleen_US

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