Beneficial effect of caffeic acid phenethyl ester CAPE on hepatocyte damage induced by bile duct ligation an electron microscopic examination

Yükleniyor...
Küçük Resim

Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Ultrastructural Pathology, 34:273–278, 2010.

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Recently the authors have reported the potent beneficial effect of caffeic acid phenethyl ester (CAPE) on cholestatic oxidative liver injury induced by acute bile ligation in Swiss albino rats. Herein, they report the ultrastructural hepatocellular alterations induced by acute bile duct ligation and the effect of CAPE administration on these alterations. Bile duct ligation resulted in many degenerative changes, such as vacuolization, mitochondrial degeneration, endoplasmic reticulum dilatation, and lysosome accumulation within the cytoplasm of hepatocytes. Mitochondrial degeneration was also observed within the cytoplasm of the cells of biliary ductular epithelium. CAPE potentially protected the hepatocytes from the cholestasis-induced cellular injury

Açıklama

Ultrastructural Pathology, 34:273–278, 2010.

Anahtar Kelimeler

Bile duct ligation, Caffeic acid phenethyl ester (CAPE), Cholestasis, Ultrastructure

Kaynak

Ultrastructural Pathology, 34:273–278, 2010.

WoS Q Değeri

Scopus Q Değeri

Cilt

34

Sayı

0

Künye

Eşrefoğlu, M., & Ara, C. (2010). Beneficial Effect Of Caffeic Acid Phenethyl Ester Cape On Hepatocyte Damage İnduced By Bile Duct Ligation An Electron Microscopic Examination. Ultrastruct Pathol, 0–0.