Effect of bilirubin in ischemia reperfusion injury on rat small intestine

dc.authorid113496en_US
dc.authorid116701en_US
dc.authorid113830en_US
dc.authorid10026en_US
dc.contributor.authorÖzcan, Canan Ceran
dc.contributor.authorSönmez, Kaan
dc.contributor.authorTürkyılmaz, zafer
dc.contributor.authorDemiroğulları, Billur
dc.contributor.authorDursun, Ayşe
dc.date.accessioned2017-12-15T08:14:37Z
dc.date.available2017-12-15T08:14:37Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.descriptionJournal of Pediatric Surgery, Vol 36, No 12 (December), 2001: pp 1764-1767.en_US
dc.description.abstractPurpose: The aim of this study was to determine the effects of bilirubin in experimental small intestinal ischemia/reperfusion (I/R) injury in rats. Methods: Thirty rats were divided into 5 groups (n 5 6). In group S, saline and in group B, bilirubin, 20 mg/kg were infused via the jugular vein without an additional procedure. In groups S-IR, saline, B1-IR and B2-IR, 10 and 20 mg/kg/h of bilirubin were infused for 2 hours, respectively. In these groups, an I/R procedure was done after infusions by occluding the superior mesenteric artery for 45 minutes followed by 1 hour of reperfusion. After reperfusion, the small intestines were resected for histopathologic and malondialdehyde (MDA) assessments. Mucosal lesions were scored between 0 and 5. Malondialdehyde levels and histopathologic grades were analyzed statistically.en_US
dc.identifier.citationCeran Özcan, C., Sönmez, K., Türkyılmaz, Z., Billur, Demiroğulları, Dursun, A., Ersel, D., … Nuri, K. (2001). Effect Of Bilirubin İn İschemia Reperfusion İnjury On Rat Small İntestine. Journal Of Pediatric Surgery, 36(12), 1764–1767.en_US
dc.identifier.doi10.1053/jpsu.2001.28816en_US
dc.identifier.endpage1767en_US
dc.identifier.issue12en_US
dc.identifier.startpage1764en_US
dc.identifier.urihttps://ac.els-cdn.com
dc.identifier.urihttps://hdl.handle.net/11616/7893
dc.identifier.volume36en_US
dc.language.isoenen_US
dc.publisherJournal of Pediatric Surgeryen_US
dc.relation.ispartofJournal of Pediatric Surgeryen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBilirubinen_US
dc.subjectİschemiaen_US
dc.subjectReperfusion injuryen_US
dc.subjectİntestineen_US
dc.titleEffect of bilirubin in ischemia reperfusion injury on rat small intestineen_US
dc.typeArticleen_US

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