Effect of bilirubin in ischemia reperfusion injury on rat small intestine
dc.authorid | 113496 | en_US |
dc.authorid | 116701 | en_US |
dc.authorid | 113830 | en_US |
dc.authorid | 10026 | en_US |
dc.contributor.author | Özcan, Canan Ceran | |
dc.contributor.author | Sönmez, Kaan | |
dc.contributor.author | Türkyılmaz, zafer | |
dc.contributor.author | Demiroğulları, Billur | |
dc.contributor.author | Dursun, Ayşe | |
dc.date.accessioned | 2017-12-15T08:14:37Z | |
dc.date.available | 2017-12-15T08:14:37Z | |
dc.date.issued | 2001 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description | Journal of Pediatric Surgery, Vol 36, No 12 (December), 2001: pp 1764-1767. | en_US |
dc.description.abstract | Purpose: The aim of this study was to determine the effects of bilirubin in experimental small intestinal ischemia/reperfusion (I/R) injury in rats. Methods: Thirty rats were divided into 5 groups (n 5 6). In group S, saline and in group B, bilirubin, 20 mg/kg were infused via the jugular vein without an additional procedure. In groups S-IR, saline, B1-IR and B2-IR, 10 and 20 mg/kg/h of bilirubin were infused for 2 hours, respectively. In these groups, an I/R procedure was done after infusions by occluding the superior mesenteric artery for 45 minutes followed by 1 hour of reperfusion. After reperfusion, the small intestines were resected for histopathologic and malondialdehyde (MDA) assessments. Mucosal lesions were scored between 0 and 5. Malondialdehyde levels and histopathologic grades were analyzed statistically. | en_US |
dc.identifier.citation | Ceran Özcan, C., Sönmez, K., Türkyılmaz, Z., Billur, Demiroğulları, Dursun, A., Ersel, D., … Nuri, K. (2001). Effect Of Bilirubin İn İschemia Reperfusion İnjury On Rat Small İntestine. Journal Of Pediatric Surgery, 36(12), 1764–1767. | en_US |
dc.identifier.doi | 10.1053/jpsu.2001.28816 | en_US |
dc.identifier.endpage | 1767 | en_US |
dc.identifier.issue | 12 | en_US |
dc.identifier.startpage | 1764 | en_US |
dc.identifier.uri | https://ac.els-cdn.com | |
dc.identifier.uri | https://hdl.handle.net/11616/7893 | |
dc.identifier.volume | 36 | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journal of Pediatric Surgery | en_US |
dc.relation.ispartof | Journal of Pediatric Surgery | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Bilirubin | en_US |
dc.subject | İschemia | en_US |
dc.subject | Reperfusion injury | en_US |
dc.subject | İntestine | en_US |
dc.title | Effect of bilirubin in ischemia reperfusion injury on rat small intestine | en_US |
dc.type | Article | en_US |