Successful living donor liver transplantation of fulminant liver failure due to isoniazid prophylaxis

Küçük Resim Yok

Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Case Reports

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Progressive liver failure is rarely seen in tuberculosis chemoprophylaxis with isoniazid. We present a case of a 32-year-old woman admitted to our clinic reporting abdominal pain, nausea and vomiting for 2 days. The initial diagnosis was fulminant toxic hepatitis due to isoniazid chemoprophylaxis, which was treated successfully with living donor transplantation. Tuberculosis continues to be a significant public health problem. Isoniazid-related hepatotoxicity is extremely rare in adults. The only treatment in cases of fulminant liver failure is orthotopic liver transplantation from a deceased or living donor. If a deceased donor is not available or the patient refuses this treatment, living donor transplantation is the only choice. Although rare, isoniazid used as protective therapy for pulmonary tuberculosis can lead to fulminant liver failure. When cadaveric liver transplantation is not available, living donor liver transplantation is vital.

Açıklama

Anahtar Kelimeler

Kaynak

Case Reports

WoS Q Değeri

Scopus Q Değeri

Cilt

3

Sayı

Künye

Çakır, T. Ara, C. Soyer, H. V. Koç, S. (2015). Successful living donor liver transplantation of fulminant liver failure due to isoniazid prophylaxis. Case Reports. 3.