Evaluation of the effectiveness of different hemostatics and bioactive materials on the success of vital pulp therapy

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dc.authoridCandan, Merve/0000-0002-9839-871X
dc.authoriddemir, pınar/0000-0003-2030-5429
dc.authoridGÖZE, Ömer Fahrettin/0009-0004-2581-8025
dc.authorwosidCandan, Merve/ABH-1843-2020
dc.authorwosiddemir, pınar/AAE-7027-2020
dc.authorwosidGÖZE, Ömer Fahrettin/JUV-5508-2023
dc.contributor.authorSaygin, Aysegul Goze
dc.contributor.authorUnal, Murat
dc.contributor.authorCandan, Merve
dc.contributor.authorDemir, Pinar
dc.contributor.authorAkinci, Levent
dc.contributor.authorGoze, Omer Fahrettin
dc.date.accessioned2024-08-04T20:58:45Z
dc.date.available2024-08-04T20:58:45Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The aim of this study was to evaluate the response of the pulp in combination of hemostatic agents with pulp capping materials (PCMs). Material and Methods: A total of 96 rats were used. Two molar teeth of each rat were included and all groups were created of 4 animals. In the occlusal cavities of the teeth, pulp perforations were performed for direct pulp capping. Thereafter, three different agents, which were forming the main groups [Group1: Sterile saline, Group2: Sodium hypochlorite, Group3 :Mecsina Hemostopper] at different periods of time used on pulp perforations and according to PCMs coated on the exposed pulp area, were divided into subgroups (Dycal, Biodentine, Theracal, and MTA Repair HP). Subsequently, all groups were left for two different waiting periods of 7 and 28 days. Half of the rats were sacrificed on the 7th and the remaining half were sacrificed on the 28th day, followed by micro-CT and histological analyzes. Results: When the results of the study were examined, a statistical difference was observed between groups in terms of dentine bridge (DB) formation on the 7th and 28th days, while there was no statistical difference between inflammatory cell response and DB quality. Micro-CT images showed no formation of DB on the 7th day, while DB formation was observed on the 28th day on specimens. Discussion: The combination of MHS and NaOCl may be preferable in order to provide pulp bleeding control in dental applications.en_US
dc.description.sponsorshipSivas Cumhuriyet University Scientific Research [Di-220]en_US
dc.description.sponsorshipThis study was supported by Sivas Cumhuriyet University Scientific Research with Di-220 project number.en_US
dc.identifier.doi10.4328/ACAM.20979
dc.identifier.endpage445en_US
dc.identifier.issn2667-663X
dc.identifier.issue4en_US
dc.identifier.startpage440en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20979
dc.identifier.urihttps://hdl.handle.net/11616/103143
dc.identifier.volume13en_US
dc.identifier.wosWOS:000782138400020en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBioactive Materialsen_US
dc.subjectDirect Pulp Cappingen_US
dc.subjectHemostatic agentsen_US
dc.subjectHistologyen_US
dc.subjectMicro-CTen_US
dc.titleEvaluation of the effectiveness of different hemostatics and bioactive materials on the success of vital pulp therapyen_US
dc.typeArticleen_US

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