ABO incompatible liver transplantation in acute and acute on chronic liver failure

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dc.contributor.authorYılmaz, Sezai
dc.contributor.authorAydın, Cemalettin
dc.contributor.authorIşık, Burak
dc.contributor.authorKayaalp, Cüneyt
dc.contributor.authorYılmaz, Mehmet
dc.contributor.authorAra, Cengiz
dc.contributor.authorKutlu, Ramazan
dc.contributor.authorBayındır, Yaşar
dc.contributor.authorErsan, Veysel
dc.date.accessioned2018-02-06T11:53:43Z
dc.date.available2018-02-06T11:53:43Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.descriptionHepatogastroenterology. 2013 Jul-Aug;60(125):1189-93.en_US
dc.description.abstractAbstract BACKGROUND/AIMS: ABO-incompatible (ABO-I) liver transplantation (LTx) may be mandatory in urgent conditions such as acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) when deceased donor (DD) is unavailable or living donor (LD) selection is limited. This study specifically addresses the problem of urgent ABO-I LTx in critically ill adult patients having ALF or severely decompensated end-stage liver disease. METHODOLOGY: This series included 16 patients, 10 underwent ABO-I LD LTx and 6 underwent 7 ABO-I DD LTx. Multiple sessions of plasmapheresis reduced isoaglutinin titres to 1/16 or below, before and after LTx. RESULTS: Mean follow-up period was 10.37 months (1 to 38). Median for MELD scores was 22.5 (17 to 30). Median survival was 9 months and mean survival was 19.5 months. Hospital mortality was 3 (18.7%). Two patients died due to small for size graft syndrome and cerebrovascular bleeding respectively. Hepatic artery thrombosis developed in 3 patients. Two of them died at postoperative 4th and 9th months. Third patient is still alive with hepatic necrosis problem. CONCLUSIONS: ABO-I LTx remains an important and unavoidable therapeutic option in adult patients with ALF or ACLF and urgent need for an allograft without the possibility to allocate a blood group compatible liver graft.en_US
dc.identifier.citationS. Yılmaz Et Al., “Abo İncompatible Liver Transplantation İn Acute And Acute On Chronic Liver Failure ,” Hepatogastroenterology, Pp. 0–0, 2013.en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pubmed/23478144
dc.identifier.urihttps://hdl.handle.net/11616/8044
dc.identifier.volume0en_US
dc.language.isoenen_US
dc.publisherHepatogastroenterologyen_US
dc.relation.ispartofHepatogastroenterologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleABO incompatible liver transplantation in acute and acute on chronic liver failureen_US
dc.typeArticleen_US

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