Assessment of the relationship between clinical and histopathological features in cases of thyroidectomy
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
EDIZIONI LUIGI POZZI, VIA PANAMA 68, 00198 ROME, ITALY
Erişim Hakkı
info:eu-repo/semantics/restrictedAccess
Özet
Aim: The aim of this study is to evaluate the relationship between clinical parameters and ultimate histopathologic features of patients underwent thyroid surgery.
METHOD: Demographic and clinicopathologic parameters of patients who underwent thyroid surgery for benign or malignant disease in our clinic between June 2006 and March 2014 were retrospectively reviewed. Pearson's Chi-Square, Independent Sample T test, ROC Curve and Youden J Index were used to investigate whether there was any relationship between the clinical parameters and permanent histopathologic features of patients.
RESULTS: A total of 3059 patients (Benign: 2727; Malign: 332) aged between 15 and 90 years were reviewed. The patients age was higher in malign group (mean +/- SD: 468 +/- 4.2) than benign group (mean +/- SD: 43.7 +/- 12.9 yr) and this difference was statistically significant (p <0.001). The nodule diameter (mean +/- SD: 30.8 +/- 13.5 mm) was greater in malign group than the benign group (mean +/- SD: 28.3 +/- 13.4 mm) and this difference was statistically significant (p = 0.002). The sensitivity and specificity rates of the most appropriate cut-off point (> 26 mm) for the nodule size were 60% and 49.05%, respectively. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of FNAB were calculated as 4.17 %, 100 %, 100 %, 89.96% and 90 %, respectively.
CONCLUSION: This study showed that higher age and greater nodule diameter (> 26 mm) are associated with malignancy
Açıklama
Anahtar Kelimeler
Fıne-Needle-Aspıratıon, Multınodular Goıter, Nodule Sıze, Cancer, Malıgnancy, Rısk, Ultrasound, Dısease, Thyroıdıtıs, Pretordıc
Kaynak
Annalı ıtalıanı dı chırurgıa
WoS Q Değeri
Scopus Q Değeri
Cilt
89
Sayı
3
Künye
Akbulut, S. (2018). Assessment of the relationship between clinical and histopathological features in cases of thyroidectomy. Cilt:89 Sayı:3, 199-205 ss.
