SEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN PATIENTS WITH GILBERT'S SYNDROME

dc.authoridbilgic, yılmaz/0000-0002-2169-5548
dc.authoridKeskin, Muharrem/0000-0002-5696-4752
dc.authoridBasturk, Abdulkadir/0000-0003-1864-0316
dc.authorwosidKeskin, Muharrem/HGE-1953-2022
dc.authorwosidbilgic, yılmaz/ABI-6432-2020
dc.authorwosidKeskin, Muharrem/AAF-7000-2021
dc.authorwosidBasturk, Abdulkadir/B-1962-2018
dc.contributor.authorKutlu, Orkide
dc.contributor.authorKeskin, Muharrem
dc.contributor.authorBasturk, Abdulkadir
dc.contributor.authorEcirli, Samil
dc.contributor.authorBilgic, Yilmaz
dc.contributor.authorFisekci Oktar, Sevil
dc.date.accessioned2024-08-04T21:01:09Z
dc.date.available2024-08-04T21:01:09Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractFamilial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by fever and accompanying attacks of serositis. Cytokines such as IL-6, TNF-alpha, IL-1 beta are known to play an active role in FMF pathogenesis. Gilbert's syndrome, is a clinical condition that results indirect hyperbilirubinemia during febrile illness, surgery, vomiting and prolonged fasting period because of inhibition of UDP-glucuronide transferase activity. Increased bilirubin levels during FMF attack is caused suppression of UDP-glucuronide transferase activity by cytokines involved in the pathogenesis of FMF. Here, we report a patient who had serious indirect bilirubin elevation during an attack of FMF.en_US
dc.identifier.endpage132en_US
dc.identifier.issn1305-6433
dc.identifier.issn1305-6441
dc.identifier.issue3en_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/11616/104122
dc.identifier.volume79en_US
dc.identifier.wosWOS:000408441500006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherIstanbul Univ, Faculty Medicine, Publishing Officeen_US
dc.relation.ispartofJournal of Istanbul Faculty of Medicine-Istanbul Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectFMFen_US
dc.subjectindirect bilirubinemiaen_US
dc.subjectGilbert's Syndromeen_US
dc.titleSEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN PATIENTS WITH GILBERT'S SYNDROMEen_US
dc.typeArticleen_US

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