The effect of the use of herbal supply on daily life activities containing OTC (chondroitin sulfate

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dc.authoridTURKMEN, Ersen/0000-0002-5536-6793
dc.authoridÇanakcı, Mehmet/0000-0002-3878-562X
dc.authorwosidTURKMEN, Ersen/KPA-4185-2024
dc.authorwosidÇanakcı, Mehmet/AAJ-8649-2020
dc.contributor.authorSevimli, Resit
dc.contributor.authorGuler, Ahmet
dc.contributor.authorCanakci, Mehmet
dc.contributor.authorEmeli, Adem
dc.contributor.authorTurkmen, Ersen
dc.date.accessioned2024-08-04T21:01:26Z
dc.date.available2024-08-04T21:01:26Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: In this study, we aimed to compare pain, functional capacity, and quality of life of patients with knee osteoarthritis (OA), determine the factors affecting them, and investigate the effect of over-the-counter (OTC)-containing herbal supplementation on daily living activities in patients with knee OA. Materials and Methods: The study included 102 patients with the diagnosis of knee OA according to the American College of Rheumatology (ACR) criteria who were admitted to our orthopedics and traumatology outpatient clinic between March 2019 and September 2019. Demographic data were recorded. The visual analog scale (VAS), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), medical outcomes study short-form health survey (SF-36) were used. The Kellgren-Lawrence scale was used for radiological evaluation. Information about the patients was determined by the questionnaire method and the patients were evaluated according to recruitment/exclusion criteria. In the study group, 102 patients with knee OA were included. On the other hand, 100 patients received a placebo as a control group. After three months of OTC supplementation, daily life activities and functional tests were performed and data were collected. Both subjective and objective data were calculated, compared, and analyzed. Results: It was observed that more than 80% of the patients with OA included in the study relieved pain with our food supplement components. There was an improvment in functional abilities of the patients with chronic OA as compared to standard medical treatment, and the pain level decreased significantly with test scores and scales after supplementary foods. The secondary endpoint was also noticed. We noticed that our subjects actually lost an average of 1.5 kg over the course of the study. Discussion: OA is the most common form of arthritis and the leading cause of disability among middle-aged and elderly people. We can develop theoretical strategies for primary prevention of joint damage through the reduction of obesity and joint trauma in particular. Effective chondroprotective therapies will be most useful when applied to high-risk individuals before the emergence of symptomatic OA. Conclusion: We concluded that food supplementation that was used in our study seemed to be beneficial in patients with knee ailments such as OA. It was equally interesting to observe that the majority of patients lost weight while taking these supplements. Although the study was underpowered, it shed light on supplements containing glucosamine. We believe that further larger series studies in the near future can help us to obtain more objective findings.en_US
dc.identifier.doi10.4328/ACAM.20074
dc.identifier.endpage256en_US
dc.identifier.issn2667-663X
dc.identifier.issue4en_US
dc.identifier.startpage252en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20074
dc.identifier.urihttps://hdl.handle.net/11616/104381
dc.identifier.volume11en_US
dc.identifier.wosWOS:000572683500002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOsteoarthritisen_US
dc.subjectPainen_US
dc.subjectHerbalen_US
dc.subjectOTCen_US
dc.subjectChondroitin Sulfateen_US
dc.subjectGlucosamineen_US
dc.subjectSupplementationen_US
dc.subjectActivitiesen_US
dc.titleThe effect of the use of herbal supply on daily life activities containing OTC (chondroitin sulfateen_US
dc.typeArticleen_US

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