Assessment of the levels of nitric oxide (NO) in chronic diarrhea patients infected with Giardia intestinalis

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dc.authoridözyalın, fatma/0000-0001-6486-6389
dc.authoridÖzyalın, Fatma/0000-0001-6486-6389;
dc.authorwosidözyalın, fatma/ABA-5258-2020
dc.authorwosidÖzyalın, Fatma/ABC-7193-2020
dc.authorwosidkaya, ozlem/KFS-7716-2024
dc.contributor.authorKaya, Ozlem M. Aycan
dc.contributor.authorAtambay, Metin
dc.contributor.authorYula, Erkan
dc.contributor.authorOzyalin, Fatma
dc.contributor.authorMotor, Vicdan Koksaldi
dc.contributor.authorMotor, Sedat
dc.contributor.authorCelik, Murat
dc.date.accessioned2024-08-04T20:57:12Z
dc.date.available2024-08-04T20:57:12Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractGiardia intestinalis is an enteric pathogen causing certain digestive disorders by attaching itself on the human intestine and, especially on the duodenum. It is reported that there is a strong relationship between the nitric oxide (NO) level and the clinical prognosis of the infection in infections of G. intestinalis. The aim of the study was to investigate serum NO levels in samples taken from patients with G. intestinalis detected in the microscopic stool examination and from the control group consisting of healthy people and the presence of any relationship with Giardiosis. The study consisted of 60 patients diagnosed with G. intestinalis in microscopic stool examination, [31 (51.7%) male, 29 (48.3%) female] and 60 healthy people [28 (46.7% male, 32 (53.5%) female] as the control group. All patients in the patient group with gastrointestinal symptoms had chronic diarrhea and cysts and trophozoites were observed in microscopic examination of the feces in all of them. Measurement of serum NO level was performed using Cortas method. When the data were evaluated by T-test in the Independent Groups, NO levels in the patient group was found low at a statistically significant level. In Giardiosis, the decline in the NO level suggested that the disease causes a more severe clinical presentation. In addition to this, we consider it necessary that extensive experimental or clinical studies be conducted on the subject.en_US
dc.identifier.doi10.5897/AJMR12.547
dc.identifier.endpage3553en_US
dc.identifier.issn1996-0808
dc.identifier.issue14en_US
dc.identifier.startpage3550en_US
dc.identifier.urihttps://doi.org/10.5897/AJMR12.547
dc.identifier.urihttps://hdl.handle.net/11616/102421
dc.identifier.volume6en_US
dc.identifier.wosWOS:000303823800025en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.ispartofAfrican Journal of Microbiology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGiardia intestinalisen_US
dc.subjectnitric oxideen_US
dc.subjectdiarrheaen_US
dc.subjectprognosisen_US
dc.titleAssessment of the levels of nitric oxide (NO) in chronic diarrhea patients infected with Giardia intestinalisen_US
dc.typeArticleen_US

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