Complement and immunoglobulin levels in serum and ascitic fluid of patients with spontaneous bacterial peritonitis, malignant ascites, and tuberculous peritonitis

Küçük Resim Yok

Tarih

2002

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Lippincott Williams & Wilkins

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background. We determined complement and immunoglobulin levels in ascitic-fluid and serum of 47 patients with spontaneous bacterial peritonitis, malignant ascites, or tuberculous ascites. Methods. Paracentesis was done to confirm the underlying cause of ascites. Biochemical, hematologic, and microbiologic investigations were also done. Results. The highest serum and ascitic fluid C3 and C4 levels and ascitic fluid IgM, IgA, and IgG levels were found in patients with tuberculosis. Ascitic fluid C3 level was found to be higher in the tuberculous group than in the patients with spontaneous bacterial peritonitis or malignant ascites. Ascitic fluid C4 levels were higher in patients with tuberculosis than in those with spontaneous bacterial peritonitis. Conclusion. We believe that further studies of the in vivo kinetics of immunoglobulins and complement in ascitic fluid of various causes are necessary for a better understanding of the host defense mechanisms of these fluids.

Açıklama

Anahtar Kelimeler

Opsonic Activity, Antimicrobial Activity, Cirrhotic-Patients, Liver-Disease, Activation, Bacteremia, Pathway, Cell

Kaynak

Southern Medical Journal

WoS Q Değeri

Q2

Scopus Q Değeri

Cilt

95

Sayı

10

Künye