Prognosis of hospitalized patients with community-acquired pneumonia

dc.contributor.authorYalçınsoy, Murat
dc.date.accessioned2019-07-24T06:31:20Z
dc.date.available2019-07-24T06:31:20Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: The long-term prognosis of patients with community-acquired pneumonia (CAP) has attracted increasing interest in recent years. The objective of the present study is to investigate the short and long-term outcomes in hospitalized patients with CAP and to identify the predictive factors associated with mortality. Patients and methods: The study was designed as a retrospective, multicenter, observational study. Hospitalized patients with CAP, as recorded in the pneumonia database of the Turkish Thoracic Society between 2011 and 2013, were included. Short-term mortality was defined as 30-day mortality and long-term mortality was assessed from those who survived 30 days. Predictive factors for short- and long-term mortality were analyzed. Results: The study included 785 patients, 68% of whom were male and the mean age was 67 +/- 16 (18-92). The median duration of follow-up was 61.2 +/- 11.8 (37-90) months. Thirty-day mortality was 9.2% and the median survival of patients surviving 30 days was 62.8 +/- 4.4 months. Multivariate analysis revealed that advanced age, the absence of fever, a higher Charlson comorbidity score, higher blood urea nitrogen (BUN)/albumin ratios and lower alanine aminotransferase (ALT) levels were all predictors of long-term mortality. Conclusion: Long-term mortality following hospitalization for CAP is high. Charlson score and lack of fever are potential indicators for decreased long-term survival. As novel parameters, baseline BUN/albumin ratios and ALT levels are significantly associated with late mortality. Further interventions and closer monitoring are necessary for such subgroups of patients. (C) 2017 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L.U.en_US
dc.identifier.citationYalçınsoy, M. (2018). Prognosis of hospitalized patients with community-acquired pneumonia. Cilt:24 Sayı:3, 164-169 ss.en_US
dc.identifier.doi10.1016/j.rppnen.2017.07.010en_US
dc.identifier.endpage169en_US
dc.identifier.issue3en_US
dc.identifier.startpage164en_US
dc.identifier.urihttps://hdl.handle.net/11616/12892
dc.identifier.volume24en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSen_US
dc.relation.ispartofPulmonologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLong-Term Mortalıtyen_US
dc.subjectFollow-Upen_US
dc.subjectPopulatıonen_US
dc.subjectCohorten_US
dc.subjectRısken_US
dc.subjectValıdatıonen_US
dc.subjectAdultsen_US
dc.subjectManagementen_US
dc.subjectMorbıdıtyen_US
dc.subjectSeverıtyen_US
dc.titlePrognosis of hospitalized patients with community-acquired pneumoniaen_US
dc.typeArticleen_US

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