Potential Risk Factors for In-Hospital Mortality in Patients with Moderate-to-Severe Blunt Multiple Trauma Who Survive Initial Resuscitation

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dc.authoridOguzturk, Hakan/0000-0002-9800-1428
dc.authoridYucel, Neslihan/0000-0001-5845-2614
dc.authoridmemişoğlu, funda/0000-0003-3905-1182;
dc.authorwosidOguzturk, Hakan/AAC-3915-2021
dc.authorwosidYucel, Neslihan/ABI-3412-2020
dc.authorwosidoguzturk, hakan/Q-6242-2019
dc.authorwosidmemişoğlu, funda/AAA-4392-2021
dc.authorwosidbıçakcıoğlu, murat/ABB-5579-2020
dc.contributor.authorYucel, Neslihan
dc.contributor.authorDemir, Tuba Ozturk
dc.contributor.authorDerya, Serdar
dc.contributor.authorOguzturk, Hakan
dc.contributor.authorBicakcioglu, Murat
dc.contributor.authorYetkin, Funda
dc.date.accessioned2024-08-04T21:00:11Z
dc.date.available2024-08-04T21:00:11Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction. The aim was to identify risk factors that influence in-hospital mortality for patients with moderate-to-severe blunt multiple trauma (BMT) who survive initial resuscitation. Methods. The prospective study involved 195 adult patients with BMT who were admitted to a referral hospital's emergency department (ED) betweenMay 1, 2015, and May 31, 2016. Results. Forty-three (22%) of the 195 patients died in hospital. Multivariate analysis identified low blood pH (odds ratio [OR] 6.580, 95% confidence interval [CI] 1.12-38.51), high serumlactate level (OR 1.041, 95% CI 1.01-1.07), high ISS (OR 1.109, 95% CI 1.06-1.16), high APACHE II score (OR 1.189, 95% CI 1.07-1.33), traumatic brain injury (TBI) (OR 4.358, 95% CI 0.76-24.86), severe hemorrhage (OR 5.314, 95% CI 1.07-26.49), and coagulopathy (OR 5.916, 95% CI 1.17-29.90) as useful predictors of acute in-hospital mortality. High ISS (OR 1.047, 95% CI 1.02-1.08), TBI (OR 8.922, 95% CI 2.57-31.00), sepsis (OR 4.956, 95% CI 1.99-12.36), acute respiratory distress syndrome (ARDS) (OR 8.036, 95% CI 1.85-34.84), respiratory failure (OR 9.630, 95% CI 2.64-35.14), renal failure (OR 74.803, 95% CI 11.34-493.43), and multiple organ failure [MOF] (OR 10.415, 95% CI 4.48-24.24) were risk factors for late in-hospital mortality. High Glasgow Coma Scale (GCS) was a good predictor for survival at 2, 7, and 28 or more days of hospitalization (OR 0.708 and 95% CI 0.56-0.09; OR 0.835 and 95% CI 0.73-0.95; OR 0.798 and 95% CI 0.71-0.90, resp.). Conclusion. Several factors signal poor short-term outcome for patients who present to the ED with moderate-to-severe BMT: low blood pH, high serum lactate level, presence of TBI, severe hemorrhage, coagulopathy, organ failure (respiratory, renal, and MOF), and ARDS. For this patient group, ISS and APACHE II scores might be helpful for stratifying by mortality risk, and GCS might be a good predictor for survival.en_US
dc.identifier.doi10.1155/2018/6461072
dc.identifier.issn2090-2840
dc.identifier.issn2090-2859
dc.identifier.pmid30595921en_US
dc.identifier.urihttps://doi.org/10.1155/2018/6461072
dc.identifier.urihttps://hdl.handle.net/11616/103877
dc.identifier.volume2018en_US
dc.identifier.wosWOS:000453252200001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofEmergency Medicine Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRespiratory-Distress-Syndromeen_US
dc.subjectOrgan Failureen_US
dc.subjectBase Deficiten_US
dc.subjectEarly Coagulopathyen_US
dc.subjectEnd-Pointsen_US
dc.subjectInjuryen_US
dc.subjectScoreen_US
dc.subjectEpidemiologyen_US
dc.subjectPredictorsen_US
dc.subjectLactateen_US
dc.titlePotential Risk Factors for In-Hospital Mortality in Patients with Moderate-to-Severe Blunt Multiple Trauma Who Survive Initial Resuscitationen_US
dc.typeArticleen_US

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