THE EFFECT OF RADIATION ON ANTIOXIDANT SYSTEM OF ESCHERICHIA COLI AND RADIATION RESISTANT DEINOCOCCUS RADIODURANS

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dc.authoridÖZBEY, Elif/0000-0001-7215-1922
dc.authoridAsma, Dilek/0000-0002-3866-3016
dc.authorwosidÖZBEY, Elif/AAJ-5577-2021
dc.authorwosidAsma, Dilek/AAA-5294-2021
dc.contributor.authorOzbey, Elif
dc.contributor.authorAsma, Dilek
dc.date.accessioned2024-08-04T21:01:25Z
dc.date.available2024-08-04T21:01:25Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn last 30-35 years, it has been discovered that many organisms can live in environments considered as extreme for mankind. Since these microorganisms can live in the extreme environments, they are named as extremophiles. One of the discovered microorganisms, Deinococcus radiodurans, had drawn attention for its extraordinary capabilities and its potential of infinity. D. radiodurans is resistant to genotoxic chemicals, oxidative damage, high-level ionization, ultraviolet radiation and dehydration. Because of these features one can name it polyextremophilic. In recent years, studies on bioremediation and related to heavy metal and detoxification of xenobiotics which cause serious environment problems, as well as genetic engineering, have been intense. However, the reactive oxygen species, induced by UV and their effects, their cellular defense mechanisms against ROS and about antioxidative systems responsible for cleaning of reactive oxygen species enough research has not been made.To this end; in Ecsherichia coli and radiation-resistant D. radiodurans bacteria were compared and tested effects on levels reduced glutathione (GSH) and antioxidant system of radiation. In both bacteria, enzyme activity and GSH levels has been determined after the different doses of gamma radiation applications. In the end of our study, high activities in enzyme especially superoxide dismutase and catalase of D. radiodurans were observed depending on the different doses gamma radiation applications. We were also observed that GSH quantity and other enzymes had a low activity in the cell. Moreover, it was determined that enzyme and GSH levels were decreased in E. coli depending on the radiation levels.en_US
dc.description.sponsorshipInonu University Academic Research Project Uniten_US
dc.description.sponsorshipWe thank Sureyya NUR for her generous support. This work was supported by the Inonu University Academic Research Project Unit.en_US
dc.identifier.endpage6133en_US
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue8en_US
dc.identifier.startpage6125en_US
dc.identifier.urihttps://hdl.handle.net/11616/104366
dc.identifier.volume28en_US
dc.identifier.wosWOS:000480511400050en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherParlar Scientific Publications (P S P)en_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDeinococcus radioduransen_US
dc.subjectRadiationen_US
dc.subjectOxidative stressen_US
dc.subjectCatalaseen_US
dc.subjectGlutathione reductaseen_US
dc.subjectGlutathione S- transferaseen_US
dc.titleTHE EFFECT OF RADIATION ON ANTIOXIDANT SYSTEM OF ESCHERICHIA COLI AND RADIATION RESISTANT DEINOCOCCUS RADIODURANSen_US
dc.typeArticleen_US

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