Successful living donor liver transplantation of fulminant liver failure due to isoniazid prophylaxis

dc.contributor.authorÇakır, Tuğrul
dc.contributor.authorAra, Cengiz
dc.contributor.authorSoyer, Hacı Vural
dc.contributor.authorKoç, Süleyman
dc.date.accessioned2018-02-06T07:00:12Z
dc.date.available2018-02-06T07:00:12Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.descriptionBMJ Case Rep 2015.en_US
dc.description.abstractProgressive liver failure is rarely seen in tuberculosis chemoprophylaxis with isoniazid. We present a case of a 32-year-old woman admitted to our clinic reporting abdominal pain, nausea and vomiting for 2 days. The initial diagnosis was fulminant toxic hepatitis due to isoniazid chemoprophylaxis, which was treated successfully with living donor transplantation. Tuberculosis continues to be a significant public health problem. Isoniazid-related hepatotoxicity is extremely rare in adults. The only treatment in cases of fulminant liver failure is orthotopic liver transplantation from a deceased or living donor. If a deceased donor is not available or the patient refuses this treatment, living donor transplantation is the only choice. Although rare, isoniazid used as protective therapy for pulmonary tuberculosis can lead to fulminant liver failure. When cadaveric liver transplantation is not available, living donor liver transplantation is vital.en_US
dc.identifier.citationTuğrul, Ç., Cengiz, A., Hacı, Vural, S., Suleyman, K. (2015). Successful living donor liver transplantation of fulminant liver failure due to isoniazid prophylaxis. BMJ Case Rep 2015.en_US
dc.identifier.doi10.1136/bcr-2015-209448en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480103/pdf/bcr-2015-209448.pdf
dc.identifier.urihttps://hdl.handle.net/11616/8040
dc.identifier.volume0en_US
dc.language.isoenen_US
dc.publisherBMJ Case Rep 2015.en_US
dc.relation.ispartofBMJ Case Rep 2015.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleSuccessful living donor liver transplantation of fulminant liver failure due to isoniazid prophylaxisen_US
dc.typeArticleen_US

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