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Öğe Injuries of large vessels in high stage neuroblastoma surgery -: A case report(Edizioni Minerva Medica, 1999) Koltuksuz, U; Gürsoy, MH; Aydinç, M; Özgen, Ü; Ege, E; Mutus, MComplete resection of the primary lesion in stage III neuroblastoma improves survival. Neuroblastoma has a tendency towards surrounding and infiltrating the large vessels, leading to injuries during tumor resection. We operated on a stage III neuroblastoma, which resulted in the right and left common iliac artery and vein damage, The right common iliac artery and, veins were repaired by end to end anastomosis, There was a long gap between the two ends of the left common iliac artery and it was repaired using a mesenteric vein (marginal vein of the colon) graft. Digital subtraction angiography performed 6 months after the operation did not reveal any stenosis or aneurysmatic changes in the anastomoses. We conclude that short segments of large vessels may be sacrificed during the resection of neuroblastomas invading the vessel wall, and the resulting defects may be repaired by end to end anastomosis, or even by substituting mesenteric vein grafts, for the pur pose of total or near total removal.Öğe Intraabdominal lymphangiomyoma in an infant with protein-losing enteropathy and hemihypertrophy(Turkish J Pediatrics, 2000) Koltuksuz, U; Özgen, Ü; Özen, S; Saraç, K; Gürsoy, MHLymphangiomyoma is an extremely rare tumor occurring exclusively in women of reproductive age. The tumor is characterized by proliferation of immature smooth muscle along the lymphatic vessels of the abdomen, thorax and lung. Although lymphangiomyoma has been reported in a young girl and a girl infant, none has been reported in boys. We report herein a case of lympangiomyoma in a two-year-old boy. The unusual presentation in this patient was that the tumor arose from the small bowel mesentery without any evidence of lung involvement. The tumor was extirpated and lymphangiomyomatosis was confirmed pathologically.Öğe Malignant melanoma of the soft parts showing calciphylaxis(Taylor & Francis Inc, 2003) Kutlu, NO; Aydin, NE; Aslan, M; Bulut, T; Özgen, ÜCalciphylaxis is a poorly understood and highly morbid syndrome of vascular calcification and skin necrosis. Hypercalcemia, hyperphosphatemia, and secondary hyperparathyroidism are the factors implicated in the pathogenesis of calciphylaxis, which is generally identified in patients with hyperparathyroidism secondary to end-stage renal disease. It has also been observed in primary hyperparathyroidism, end-stage liver disease, and rheumatoid arthritis, in the absence of renal disease. There are few case reports of calciphylaxis occurring in hypercalcemia of malignancy. An unusual case is reported of calciphylaxis associated with malignant melanoma of the soft parts in the absence of renal or parathyroid disease. This is the first reported case of this soft tissue sarcoma showing calciphylactic changes.Öğe Neutropenic enterocolitis (typhlitis) associated with infectious mononucleosis(Springer, 2006) Sigirci, A; Akinci, A; Özgen, Ü; Özen, MNeutropenic enterocolitis (typhlitis) is an unusual acute complication of neutropenia, most often associated with leukaemia and lymphoma and characterized by segmental caecal and ascending colonic ulceration that may progress to necrosis, perforation, and septicaemia. We present a unique case of an 8-year-old girl with recently diagnosed infectious mononucleosis having findings consistent with typhlitis on abdominal CT.Öğe Potential salvage therapy for accidental intrathecal vincristine administration(Karger, 2000) Özgen, Ü; Soylu, H; Önal, SÇ; Mizrak, B; Türköz, Y; Kutlu, NO; Koçak, ABackground: Accidental intrathecal vincristine (VCR) administration results in severe neurotoxicity, usually fatal in outcome. No specific therapy for initrathecal VCR toxicity has been reported so far. In our recent report, complete in vitro degradation of VCR by hypochlorous acid (HOCl) was demonstrated. Methods: In this comparative study, we examined the in vivo effectivity of HOCl in the cerebrospinal fluid of 24 New Zealand rabbits following intracisternal VCR administration. Results: There were no significant clinical or histopathologic abnormalities in the control and HOCl groups; however, multiple necrotic foci on histopathological examination of brain sections in the VCR group were determined. There were significantly lower numbers of necrotic foci in brain sections of rabbits which received HOCl administration than those without therapy. Conclusion: Our results indicate that HOCl may reduce VCR neurotoxicity. Copyright (C) 2000 S. Karger AG, Basel.Öğe Prune-belly syndrome and pulmonary hypoplasia(Blackwell Science Asia, 2001) Soylu, H; Kutlu, NO; Sönmezgöz, E; Bükte, Y; Özgen, Ü; Akinci, A[Abstract Not Available]Öğe wt1 gene expression in childhood acute leukemias(Karger, 2000) Özgen, Ü; Anak, S; Özbek, U; Sarper, N; Eryilmaz, E; Agaoglu, L; Devecioglu, Ö[Abstract Not Available]
