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    Expression of cell proliferation markers in benign, premalignant and malignant lesions and human papillomavirus isolation
    (2007) Serarslan G.; Atik E.; Otlu B.; Bakariş S.; Durmaz R.
    Background and Design: This study was designed to investigate the role of proliferation markers in various benign, premalignant and malignant skin lesions and also aimed to detect HPV positivity in these lesions. Material and Method: A total of 62 paraffin blocks [12 seborrheic keratoses (SK), 10 keratoacantoma (KA), 8 actinic keratoses (AK), 22 basal cell carcinoma (BCC), and 10 squamous cell carcinoma (SCC)] were included in the study. Specimens were studied immunohistochemically for the expression of Ki-67, p21 and bcl-2. PCR was performed to detect HPV DNA. Results: HPV positivity was detected in two tissues of BCC (HPV type-16). In the lesions, the Ki-67, p21 and bcl-2 expressions were found to be increased respectively: KA
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    Syringocystadenoma papilliferum
    (1997) Ozcan A.; Senol M.; Dogan G.; Aydin A.; Atik E.
    Syringocystadenoma papilliferum is a rare adnexal benign tumur which commonly develops from apocrine sweat glands. It is mostly seen in women. The majority of the lesions are located on the scalp and neck. They are rarely found on the trunk and the extremities. The lesion is generally found as an asymptomatic solitary plaque. A basal cell epithelioma can rarely arise in this lesion especially when exists with a nevus sebaceus. A 33-year-old woman with a syringocystadenoma papilliferum was presented and the current literature on this issue was reviewed.